Clinical Application of the Quick Sepsis-Related Organ Failure Assessment Score at Intensive Care Unit Admission in Patients with Bacteremia: A Single-Center Experience of Korea
Background We evaluated the clinical usefulness of the quick Sepsis-Related Organ Failure Assessment (qSOFA) score (based on the 2016 definition of sepsis) at intensive care unit admission in Korean patients with bacteremia. Methods We retrospectively analyzed clinical data from 236 patients between...
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| Format: | Article |
| Language: | English |
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Korean Society of Critical Care Medicine
2017-08-01
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| Series: | Korean Journal of Critical Care Medicine |
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| Online Access: | http://www.kjccm.org/upload/pdf/kjccm-2017-00241.pdf |
| _version_ | 1818084135309148160 |
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| author | Hae Jung Na Eun Suk Jeong Insu Kim Won-Young Kim Kwangha Lee |
| author_facet | Hae Jung Na Eun Suk Jeong Insu Kim Won-Young Kim Kwangha Lee |
| author_sort | Hae Jung Na |
| collection | DOAJ |
| description | Background We evaluated the clinical usefulness of the quick Sepsis-Related Organ Failure Assessment (qSOFA) score (based on the 2016 definition of sepsis) at intensive care unit admission in Korean patients with bacteremia. Methods We retrospectively analyzed clinical data from 236 patients between March 2011 and February 2016. In addition to the qSOFA, the Modified Early Warning score (MEWS) and systemic inflammatory response syndrome (SIRS) criteria were calculated. Results The patients’ median age was 69 years, and 61.0% were male. Of the patients, 127 (53.8%) had a qSOFA score ≥2 points. They had significantly higher rates of septic shock, thrombocytopenia, and hyperlactatemia, and increased requirements for ventilator care, neuromuscular blocking agents, vasopressors, and hemodialysis within 72 hours after intensive care unit admission. They also had a significantly higher 28-day mortality rate. When analyzed using common thresholds (MEWS ≥5 and ≥2 SIRS criteria), patients with a MEWS ≥5 had the same results as those with a qSOFA score ≥2 (P < 0.05). However, patients with ≥2 SIRS criteria showed no significant differences. Conclusions Our results show that a qSOFA score ≥2 at admission is a useful screening tool for predicting disease severity and medical resource usage within 72 hours after admission, and for predicting 28-day mortality rates in patients with bacteremia. In addition, qSOFA scores may be more useful than SIRS criteria in terms of prognostic utility. |
| first_indexed | 2024-12-10T19:49:04Z |
| format | Article |
| id | doaj.art-54f7807be05c481bb89ef2203581758e |
| institution | Directory Open Access Journal |
| issn | 2383-4870 2383-4889 |
| language | English |
| last_indexed | 2024-12-10T19:49:04Z |
| publishDate | 2017-08-01 |
| publisher | Korean Society of Critical Care Medicine |
| record_format | Article |
| series | Korean Journal of Critical Care Medicine |
| spelling | doaj.art-54f7807be05c481bb89ef2203581758e2022-12-22T01:35:49ZengKorean Society of Critical Care MedicineKorean Journal of Critical Care Medicine2383-48702383-48892017-08-0132324725510.4266/kjccm.2017.002411105Clinical Application of the Quick Sepsis-Related Organ Failure Assessment Score at Intensive Care Unit Admission in Patients with Bacteremia: A Single-Center Experience of KoreaHae Jung Na0Eun Suk Jeong1Insu Kim2Won-Young Kim3Kwangha Lee4 Department of Internal Medicine, Good Samsun Hospital, Busan, Korea Division of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, Pusan National University School of Medicine, Busan, Korea Division of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, Pusan National University School of Medicine, Busan, Korea Division of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, Pusan National University School of Medicine, Busan, Korea Division of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, Pusan National University School of Medicine, Busan, KoreaBackground We evaluated the clinical usefulness of the quick Sepsis-Related Organ Failure Assessment (qSOFA) score (based on the 2016 definition of sepsis) at intensive care unit admission in Korean patients with bacteremia. Methods We retrospectively analyzed clinical data from 236 patients between March 2011 and February 2016. In addition to the qSOFA, the Modified Early Warning score (MEWS) and systemic inflammatory response syndrome (SIRS) criteria were calculated. Results The patients’ median age was 69 years, and 61.0% were male. Of the patients, 127 (53.8%) had a qSOFA score ≥2 points. They had significantly higher rates of septic shock, thrombocytopenia, and hyperlactatemia, and increased requirements for ventilator care, neuromuscular blocking agents, vasopressors, and hemodialysis within 72 hours after intensive care unit admission. They also had a significantly higher 28-day mortality rate. When analyzed using common thresholds (MEWS ≥5 and ≥2 SIRS criteria), patients with a MEWS ≥5 had the same results as those with a qSOFA score ≥2 (P < 0.05). However, patients with ≥2 SIRS criteria showed no significant differences. Conclusions Our results show that a qSOFA score ≥2 at admission is a useful screening tool for predicting disease severity and medical resource usage within 72 hours after admission, and for predicting 28-day mortality rates in patients with bacteremia. In addition, qSOFA scores may be more useful than SIRS criteria in terms of prognostic utility.http://www.kjccm.org/upload/pdf/kjccm-2017-00241.pdfbacteremiaintensive care unitsmortalityprognosissepsis. |
| spellingShingle | Hae Jung Na Eun Suk Jeong Insu Kim Won-Young Kim Kwangha Lee Clinical Application of the Quick Sepsis-Related Organ Failure Assessment Score at Intensive Care Unit Admission in Patients with Bacteremia: A Single-Center Experience of Korea Korean Journal of Critical Care Medicine bacteremia intensive care units mortality prognosis sepsis. |
| title | Clinical Application of the Quick Sepsis-Related Organ Failure Assessment Score at Intensive Care Unit Admission in Patients with Bacteremia: A Single-Center Experience of Korea |
| title_full | Clinical Application of the Quick Sepsis-Related Organ Failure Assessment Score at Intensive Care Unit Admission in Patients with Bacteremia: A Single-Center Experience of Korea |
| title_fullStr | Clinical Application of the Quick Sepsis-Related Organ Failure Assessment Score at Intensive Care Unit Admission in Patients with Bacteremia: A Single-Center Experience of Korea |
| title_full_unstemmed | Clinical Application of the Quick Sepsis-Related Organ Failure Assessment Score at Intensive Care Unit Admission in Patients with Bacteremia: A Single-Center Experience of Korea |
| title_short | Clinical Application of the Quick Sepsis-Related Organ Failure Assessment Score at Intensive Care Unit Admission in Patients with Bacteremia: A Single-Center Experience of Korea |
| title_sort | clinical application of the quick sepsis related organ failure assessment score at intensive care unit admission in patients with bacteremia a single center experience of korea |
| topic | bacteremia intensive care units mortality prognosis sepsis. |
| url | http://www.kjccm.org/upload/pdf/kjccm-2017-00241.pdf |
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