Antileishmanial Activity of BNIPDaoct- and BNIPDanon-loaded Emulsomes on Leishmania infantum Parasites

Antileishmanial Activity of BNIPDaoct- and BNIPDanon-loaded Emulsomes on Leishmania infantum Parasites

Among bisnaphthalimidopropyl (BNIP) derivatives, BNIPDaoct and BNIPDanon recently came forward with antileishmanial activities beyond the standard, commercialized antileishmanial therapies. However, high-level toxicity on macrophages plus poor aqueous solubility and poor bioavailability of the compo...

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Bibliographic Details
Main Authors: Zeynep Islek, Mehmet Hikmet Ucisik, Elif Keskin, Bilgesu Onur Sucu, Ana G. Gomes‐Alves, Ana M. Tomás, Mustafa Guzel, Fikrettin Sahin
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Nanotechnology
Subjects:
bisnapthalimidopropyl (BNIP) derivatives
Leishmania infantum
nanocarrier
emulsome
antileishmanial therapy
infected macrophages
Online Access:https://www.frontiersin.org/articles/10.3389/fnano.2021.773741/full

Internet

https://www.frontiersin.org/articles/10.3389/fnano.2021.773741/full

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