Early surgical decompression within 8 hours for traumatic spinal cord injury: Is it beneficial? A meta-analysis
Introduction: The aim of this study is to evaluate whether early (<8 h) surgical decompression is better in improving neurologic outcomes than late (≥8 h) surgical decompression for traumatic spinal cord injury (tSCI). Methods: The various electronic databases were used to detect relevant article...
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| Format: | Article |
| Language: | English |
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AVES
2018-03-01
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| Series: | Acta Orthopaedica et Traumatologica Turcica |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1017995X17304881 |
| _version_ | 1797915429517131776 |
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| author | Dong-Yeong Lee Young-Jin Park Hyun-Jung Kim Hyeong-Sik Ahn Sun-Chul Hwang Dong-Hee Kim |
| author_facet | Dong-Yeong Lee Young-Jin Park Hyun-Jung Kim Hyeong-Sik Ahn Sun-Chul Hwang Dong-Hee Kim |
| author_sort | Dong-Yeong Lee |
| collection | DOAJ |
| description | Introduction: The aim of this study is to evaluate whether early (<8 h) surgical decompression is better in improving neurologic outcomes than late (≥8 h) surgical decompression for traumatic spinal cord injury (tSCI). Methods: The various electronic databases were used to detect relevant articles published up until May 2016 that compared the outcomes of early versus late surgery for tSCI. Data searching, extraction, analysis, and quality assessment were performed according to Cochrane Collaboration guidelines. The results are presented as relative ratio (RR) for binary outcomes and mean difference (MD) for continuous outcomes with 95% confidence intervals (CIs). Results: Seven studies were finally included in this meta-analysis. There were significant differences between the 2 groups in neurologic improvement (MD = 0.54, 95% CI = −18.52 to −7.02, P < 0.0001) and length of hospital stay (MD = −12.77, 95% CI = 0.34–0.74, P < 0.00001). However, no significant differences were found between the 2 groups in perioperative complications (OR = 0.95, 95% CI = 0.35–2.61, P = 0.92). Conclusions: Early surgical decompression within 8 h after tSCI was beneficial in terms of neurologic improvement compared with late surgery. Early surgical decompression (within 8 h) is recommended for patients with tSCI. Level of evidence: Level III, therapeutic study. Keywords: Spinal cord injuries, Decompression, Timing of surgery, Meta-analysis |
| first_indexed | 2024-04-10T12:41:42Z |
| format | Article |
| id | doaj.art-54fa57ad2926409a8fe9a917c76cedc0 |
| institution | Directory Open Access Journal |
| issn | 1017-995X |
| language | English |
| last_indexed | 2024-04-10T12:41:42Z |
| publishDate | 2018-03-01 |
| publisher | AVES |
| record_format | Article |
| series | Acta Orthopaedica et Traumatologica Turcica |
| spelling | doaj.art-54fa57ad2926409a8fe9a917c76cedc02023-02-15T16:14:15ZengAVESActa Orthopaedica et Traumatologica Turcica1017-995X2018-03-01522101108Early surgical decompression within 8 hours for traumatic spinal cord injury: Is it beneficial? A meta-analysisDong-Yeong Lee0Young-Jin Park1Hyun-Jung Kim2Hyeong-Sik Ahn3Sun-Chul Hwang4Dong-Hee Kim5Armed Forces Deagu Hospital, Daegu, Republic of Korea; Department of Orthopaedic Surgery and Medicine, Gyeongsang National University School of Medicine and Gyeongsang National University Hospital, Jinju, Republic of KoreaDepartment of Orthopaedic Surgery and Medicine, Gyeongsang National University School of Medicine and Gyeongsang National University Hospital, Jinju, Republic of KoreaInstitute for Evidence-based Medicine, Department of Preventive Medicine, College of Medicine, Korea University, Seoul, Republic of KoreaInstitute for Evidence-based Medicine, Department of Preventive Medicine, College of Medicine, Korea University, Seoul, Republic of KoreaDepartment of Orthopaedic Surgery and Medicine, Gyeongsang National University School of Medicine and Gyeongsang National University Hospital, Jinju, Republic of KoreaDepartment of Orthopaedic Surgery and Medicine, Gyeongsang National University School of Medicine and Gyeongsang National University Hospital, Jinju, Republic of Korea; Corresponding author. Department of Orthopaedic Surgery, Gyeongsang National University School of Medicine and Gyeongsang National University Hospital, 15, Jinju-daero 816 beon-gil, Jinju-si, Gyeongsangnam-do, 660-751, Republic of Korea. Fax: +82 55-761-9477.Introduction: The aim of this study is to evaluate whether early (<8 h) surgical decompression is better in improving neurologic outcomes than late (≥8 h) surgical decompression for traumatic spinal cord injury (tSCI). Methods: The various electronic databases were used to detect relevant articles published up until May 2016 that compared the outcomes of early versus late surgery for tSCI. Data searching, extraction, analysis, and quality assessment were performed according to Cochrane Collaboration guidelines. The results are presented as relative ratio (RR) for binary outcomes and mean difference (MD) for continuous outcomes with 95% confidence intervals (CIs). Results: Seven studies were finally included in this meta-analysis. There were significant differences between the 2 groups in neurologic improvement (MD = 0.54, 95% CI = −18.52 to −7.02, P < 0.0001) and length of hospital stay (MD = −12.77, 95% CI = 0.34–0.74, P < 0.00001). However, no significant differences were found between the 2 groups in perioperative complications (OR = 0.95, 95% CI = 0.35–2.61, P = 0.92). Conclusions: Early surgical decompression within 8 h after tSCI was beneficial in terms of neurologic improvement compared with late surgery. Early surgical decompression (within 8 h) is recommended for patients with tSCI. Level of evidence: Level III, therapeutic study. Keywords: Spinal cord injuries, Decompression, Timing of surgery, Meta-analysishttp://www.sciencedirect.com/science/article/pii/S1017995X17304881 |
| spellingShingle | Dong-Yeong Lee Young-Jin Park Hyun-Jung Kim Hyeong-Sik Ahn Sun-Chul Hwang Dong-Hee Kim Early surgical decompression within 8 hours for traumatic spinal cord injury: Is it beneficial? A meta-analysis Acta Orthopaedica et Traumatologica Turcica |
| title | Early surgical decompression within 8 hours for traumatic spinal cord injury: Is it beneficial? A meta-analysis |
| title_full | Early surgical decompression within 8 hours for traumatic spinal cord injury: Is it beneficial? A meta-analysis |
| title_fullStr | Early surgical decompression within 8 hours for traumatic spinal cord injury: Is it beneficial? A meta-analysis |
| title_full_unstemmed | Early surgical decompression within 8 hours for traumatic spinal cord injury: Is it beneficial? A meta-analysis |
| title_short | Early surgical decompression within 8 hours for traumatic spinal cord injury: Is it beneficial? A meta-analysis |
| title_sort | early surgical decompression within 8 hours for traumatic spinal cord injury is it beneficial a meta analysis |
| url | http://www.sciencedirect.com/science/article/pii/S1017995X17304881 |
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