Gelatin Nanoparticles for Complexation and Enhanced Cellular Delivery of mRNA

Gelatin Nanoparticles for Complexation and Enhanced Cellular Delivery of mRNA

Messenger RNA (mRNA) is increasingly gaining interest as a modality in vaccination and protein replacement therapy. In regenerative medicine, the mRNA-mediated expression of growth factors has shown promising results. In contrast to protein delivery, successful mRNA delivery requires a vector to ind...

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Bibliographic Details
Main Authors: Lea Andrée, Rik Oude Egberink, Josephine Dodemont, Negar Hassani Besheli, Fang Yang, Roland Brock, Sander C. G. Leeuwenburgh
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Nanomaterials
Subjects:
gelatin
gelatin nanoparticles
mRNA
mRNA delivery
endosomal escape
Online Access:https://www.mdpi.com/2079-4991/12/19/3423

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