Synchronous hepatocellular carcinoma and renal cell carcinoma in young woman with sarcoidosis: A case report
Hepatocellular carcinoma (HCC) and clear cell renal carcinoma are both frequent cancers, especially in patients with risk factors such as cirrhosis in the first case or genetic mutations such as Li-Fraumeni syndrome in the second case; however, their synchronous appearance is very rare especially in...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-01-01
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| Series: | Radiology Case Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1930043322009244 |
| _version_ | 1828126823565754368 |
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| author | Mario Simonetti, MD Francesca Cavaliere, MD Anna Pecorelli, MD Benedetta Fabbrizio, MD Francesco Vasuri, MD Rita Golfieri, MD |
| author_facet | Mario Simonetti, MD Francesca Cavaliere, MD Anna Pecorelli, MD Benedetta Fabbrizio, MD Francesco Vasuri, MD Rita Golfieri, MD |
| author_sort | Mario Simonetti, MD |
| collection | DOAJ |
| description | Hepatocellular carcinoma (HCC) and clear cell renal carcinoma are both frequent cancers, especially in patients with risk factors such as cirrhosis in the first case or genetic mutations such as Li-Fraumeni syndrome in the second case; however, their synchronous appearance is very rare especially in young patients with no apparent predisposing factors. We describe the case of a 33-year-old woman with acute pain onset in right hypochondrium. The ultrasound (US) imaging and the contrast-enhanced computed tomography (CECT) of the abdomen revealed 2 abdominal masses: one in the VI-VII segments of the liver and the other one in the right kidney. The chest CECT study, acquired for staging purpose, detected multiple micronodules with patchy peri-bronchial distribution at both lungs. At the histological examination, the tumor arising from the right kidney was finally diagnosed as clear cell renal carcinoma, whereas the tumor arising from the right lateral hepatic lobe as HCC. The histological examination of lung lesions revealed sarcoidosis granulomas. The patient is still being followed up for the occurrence of lung and lymph node metastases from HCC 14 months later. |
| first_indexed | 2024-04-11T15:40:19Z |
| format | Article |
| id | doaj.art-55012f9008124361954679c5b7d9600a |
| institution | Directory Open Access Journal |
| issn | 1930-0433 |
| language | English |
| last_indexed | 2024-04-11T15:40:19Z |
| publishDate | 2023-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Radiology Case Reports |
| spelling | doaj.art-55012f9008124361954679c5b7d9600a2022-12-22T04:15:49ZengElsevierRadiology Case Reports1930-04332023-01-01181358363Synchronous hepatocellular carcinoma and renal cell carcinoma in young woman with sarcoidosis: A case reportMario Simonetti, MD0Francesca Cavaliere, MD1Anna Pecorelli, MD2Benedetta Fabbrizio, MD3Francesco Vasuri, MD4Rita Golfieri, MD5Department of Radiology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Via Albertoni 15, 40138, Bologna, Italy; Corresponding author.Department of Radiology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Via Albertoni 15, 40138, Bologna, ItalyDepartment of Radiology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Via Albertoni 15, 40138, Bologna, ItalyDepartment of Anatomy and Pathological Histology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Via Massarenti 9, 40138, Bologna, ItalyDepartment of Anatomy and Pathological Histology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Via Massarenti 9, 40138, Bologna, ItalyDepartment of Radiology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Via Albertoni 15, 40138, Bologna, ItalyHepatocellular carcinoma (HCC) and clear cell renal carcinoma are both frequent cancers, especially in patients with risk factors such as cirrhosis in the first case or genetic mutations such as Li-Fraumeni syndrome in the second case; however, their synchronous appearance is very rare especially in young patients with no apparent predisposing factors. We describe the case of a 33-year-old woman with acute pain onset in right hypochondrium. The ultrasound (US) imaging and the contrast-enhanced computed tomography (CECT) of the abdomen revealed 2 abdominal masses: one in the VI-VII segments of the liver and the other one in the right kidney. The chest CECT study, acquired for staging purpose, detected multiple micronodules with patchy peri-bronchial distribution at both lungs. At the histological examination, the tumor arising from the right kidney was finally diagnosed as clear cell renal carcinoma, whereas the tumor arising from the right lateral hepatic lobe as HCC. The histological examination of lung lesions revealed sarcoidosis granulomas. The patient is still being followed up for the occurrence of lung and lymph node metastases from HCC 14 months later.http://www.sciencedirect.com/science/article/pii/S1930043322009244Hepatocellular carcinomaRenal cell carcinomaSynchronousYoungSarcoidosis |
| spellingShingle | Mario Simonetti, MD Francesca Cavaliere, MD Anna Pecorelli, MD Benedetta Fabbrizio, MD Francesco Vasuri, MD Rita Golfieri, MD Synchronous hepatocellular carcinoma and renal cell carcinoma in young woman with sarcoidosis: A case report Radiology Case Reports Hepatocellular carcinoma Renal cell carcinoma Synchronous Young Sarcoidosis |
| title | Synchronous hepatocellular carcinoma and renal cell carcinoma in young woman with sarcoidosis: A case report |
| title_full | Synchronous hepatocellular carcinoma and renal cell carcinoma in young woman with sarcoidosis: A case report |
| title_fullStr | Synchronous hepatocellular carcinoma and renal cell carcinoma in young woman with sarcoidosis: A case report |
| title_full_unstemmed | Synchronous hepatocellular carcinoma and renal cell carcinoma in young woman with sarcoidosis: A case report |
| title_short | Synchronous hepatocellular carcinoma and renal cell carcinoma in young woman with sarcoidosis: A case report |
| title_sort | synchronous hepatocellular carcinoma and renal cell carcinoma in young woman with sarcoidosis a case report |
| topic | Hepatocellular carcinoma Renal cell carcinoma Synchronous Young Sarcoidosis |
| url | http://www.sciencedirect.com/science/article/pii/S1930043322009244 |
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