Nogo-A-deficient transgenic rats show deficits in higher cognitive functions, decreased anxiety and altered circadian activity patterns

Nogo-A-deficient transgenic rats show deficits in higher cognitive functions, decreased anxiety and altered circadian activity patterns

Decreased levels of Nogo-A dependent signaling have been shown to affect behavior and cognitive functions. In Nogo-A knockout and knock-down laboratory rodents, behavioral alterations were observed, possibly corresponding with human neuropsychiatric diseases of neurodevelopmental origin, particularl...

Full description

Bibliographic Details
Main Authors:	Tomas ePetrasek, Iva eProkopova, Martin eSladek, Kamila eWeissova, Iveta eVojtechova, Stepan eBahnik, Anna eZemanova, Kai eSchönig, Stefan eBerger, Björn eTews, Dusan eBartsch, Martin eSchwab, Alena eSumova, Ales eStuchlik
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2014-03-01
Series:	Frontiers in Behavioral Neuroscience
Subjects:	Anhedonia Cognition Spatial learning Nogo-A passive avoidance circadian rhythmicity
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fnbeh.2014.00090/full

Similar Items

Corrigendum: "Nogo-A-deficient transgenic rats show deficits in higher cognitive functions, decreased anxiety, and altered circadian activity patterns
by: Tomas ePetrasek, et al.
Published: (2014-12-01)

N-methyl-D-aspartate receptor - nitric oxide synthase pathway in the cortex of Nogo-A-deficient rats in relation to brain laterality and schizophrenia
by: Zdena eKristofikova, et al.
Published: (2013-08-01)

Reduced expression of Nogo-A leads to motivational deficits in rats
by: Thomas eEnkel, et al.
Published: (2014-01-01)

A RAT MODEL OF ALZHEIMER´S DISEASE BASED ON ABETA42 AND PRO-OXIDATIVE SUBSTANCES EXHIBITS COGNITIVE DEFICIT AND ALTERATIONS IN GLUTAMATERGIC AND CHOLINERGIC NEUROTRANSMITTER SYSTEMS
by: Tomáš ePetrásek, et al.
Published: (2016-04-01)

Finding an optimal rehabilitation paradigm after stroke: Enhancing fiber growth and training of the brain at the right moment
by: Anna-Sophia eWahl, et al.
Published: (2014-06-01)

Paraoxonase (PON1 and PON3) polymorphisms: impact on liver expression and atorvastatin-lactone hydrolysis
by: Stephan eRiedmaier, et al.
Published: (2011-07-01)

Pathway-targeted pharmacogenomics of CYP1A2 in human liver
by: Kathrin eKlein, et al.
Published: (2010-11-01)

Evolution and structural diversification of PILS putative auxin carriers in plants
by: Elena eFeraru, et al.
Published: (2012-10-01)

Impaired top-down modulation of saccadic latencies in patients with schizophrenia but not in first-degree relatives
by: Simon eSchwab, et al.
Published: (2015-02-01)

Peroxisome proliferator-activated receptor alpha, PPARα, directly regulates transcription of cytochrome P450 CYP2C8
by: Maria eThomas, et al.
Published: (2015-11-01)

The common gut microbe Eubacterium hallii also contributes to intestinal propionate formation
by: Christina eEngels, et al.
Published: (2016-05-01)

The time-course of EEG Alpha Power Changes in Creative Ideation
by: Daniela eSchwab, et al.
Published: (2014-05-01)

FaPOD27 functions in the metabolism of polyphenols in strawberry fruit (Fragaria sp.)
by: Su-Ying eYeh, et al.
Published: (2014-10-01)

Influence of formal education on cognitive reserve in patients with multiple sclerosis
by: Ralf eLürding, et al.
Published: (2016-03-01)

Inducible gene manipulations in brain serotonergic neurons of transgenic rats.
by: Tillmann Weber, et al.
Published: (2011-01-01)

Anchoring without scale distortion
by: Štěpán Bahník
Published: (2021-01-01)

MK-801 impairs cognitive coordination on a rotating arena (Carousel) and contextual specificity of hippocampal immediate-early gene expression in a rat model of psychosis
by: Štěpán eKubík, et al.
Published: (2014-03-01)

Temporal and spatial strategies in an active place avoidance task on Carousel: a study of effects of stability of arena rotation speed in rats
by: Štěpán Bahník, et al.
Published: (2015-09-01)

Overlap of accessible information undermines the anchoring effect
by: Štěpán Bahník, et al.
Published: (2016-01-01)

No evidence of moral licensing in a laboratory bribe-taking task
by: Štěpán Bahník, et al.
Published: (2022-08-01)

Distinct effects of chronic dopaminergic stimulation on hippocampal neurogenesis and striatal doublecortin expression in adult mice
by: Rachele eSalvi, et al.
Published: (2016-03-01)

Predictors of Bribe-Taking: The Role of Bribe Size and Personality
by: Marek A. Vranka, et al.
Published: (2018-09-01)

LIGHT SHEET FLUORESCENCE MICROSCOPY COMBINED WITH OPTICAL CLEARING METHODS AS A NOVEL IMAGING TOOL IN BIOMEDICAL RESEARCH
by: Julia Bode, et al.
Published: (2017-01-01)

The effect of psilocin on memory acquisition, retrieval and consolidation in rat.
by: Lukas eRambousek, et al.
Published: (2014-05-01)

Infectious origin of Alzheimer's disease: Amyloid beta as a component of brain antimicrobial immunity.
by: Iveta Vojtechova, et al.
Published: (2022-11-01)

Cognitive skills and reading in adults with Usher syndrome type 2
by: Cecilia eHenricson, et al.
Published: (2015-03-01)

Consequences of early postnatal benzodiazepines exposure in rats. I. Cognitive-like behavior
by: Anna eMikulecka, et al.
Published: (2014-03-01)

Intestinal microbiota signatures associated with inflammation history in mice experiencing recurring colitis
by: David eBerry, et al.
Published: (2015-12-01)

GabiPD – The GABI Primary Database integrates plant proteomic data with gene-centric information
by: Björn eUsadel, et al.
Published: (2012-07-01)

Reassessing the Reassessment of suPAR in glomerular disease
by: Björn eMeijers, et al.
Published: (2015-01-01)

Genome maintenance and transcription integrity in ageing and disease
by: Stefanie eWolters, et al.
Published: (2013-02-01)

Season exerts differential effects of ocean acidification and warming on growth and carbon metabolism of the seaweed Fucus vesiculosus in the western Baltic Sea
by: Angelika eGraiff, et al.
Published: (2015-12-01)

The McGill Transgenic Rat Model of Alzheimer's Disease Displays Cognitive and Motor Impairments, Changes in Anxiety and Social Behavior, and Altered Circadian Activity
by: Tomas Petrasek, et al.
Published: (2018-08-01)

Corrigendum: Acute administration of MK-801 in ananimal model of psychosis in rats interferes with cognitively demanding forms of behavioral flexibility on a rotating arena
by: Jan eSvoboda, et al.
Published: (2015-12-01)

Acute Administration of MK-801 in an Animal Model of Psychosis in Rats Interferes with Cognitively Demanding Forms of Behavioral Flexibility on a Rotating Arena
by: Jan eSvoboda, et al.
Published: (2015-04-01)

Structural and functional reorganization of propriospinal connections promotes functional recovery after spinal cord injury
by: Linard Filli, et al.
Published: (2015-01-01)

Nogo and Nogo receptor: Relevance to schizophrenia?
by: Roman Willi, et al.
Published: (2013-06-01)

Fronto-limbic novelty processing in acute psychosis: disrupted relationship with memory performance and potential implications for delusions
by: Björn H Schott, et al.
Published: (2015-06-01)

Selection effects on dishonest behavior
by: Petr Houdek, et al.
Published: (2021-03-01)

Variations on anchoring: Sequential anchoring revisited
by: Štěpán Bahník, et al.
Published: (2019-11-01)