Oncogenic and drug-sensitive RET mutations in human epithelial ovarian cancer

Oncogenic and drug-sensitive RET mutations in human epithelial ovarian cancer

Abstract Background Epithelial ovarian cancer (EOC) is a highly lethal malignancy. Improvement in genetic characterization of EOC patients is required to propose new potential targets, since surgical resection coupled to chemotherapy, presents several limits such as cancer recurrence and drug resist...

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Bibliographic Details
Main Authors: Luyao Guan, Zhang Li, Feifei Xie, Yuzhi Pang, Chenyun Zhang, Haosha Tang, Hao Zhang, Chun Chen, Yaying Zhan, Ting Zhao, Hongyuan Jiang, Xiaona Jia, Yuexiang Wang, Yuan Lu
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
RET
Ovarian cancer
Vandetanib
Targeted therapy
Online Access:http://link.springer.com/article/10.1186/s13046-020-01557-3

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