In silico investigation of pro-arrhythmic effects of azithromycin on the human ventricle

In silico investigation of pro-arrhythmic effects of azithromycin on the human ventricle

The macrolide antibiotic azithromycin (AZM) is widely used for respiratory infections and has been suggested to be a possible treatment for the Coronavirus Disease of 2019 (COVID-19). However, AZM-associated QT interval prolongation and arrhythmias have been reported. Integrated mechanistic informat...

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Bibliographic Details
Main Authors: Yizhou Liu, Rai Zhang, Jules C. Hancox, Henggui Zhang
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Biochemistry and Biophysics Reports
Subjects:
Azithromycin
Arrhythmia
Cardiac modelling
Human ventricle
COVID-19
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580821001370

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