Risk Factors for Non-communicable Diseases in Vietnam: A Focus on Pesticides

Agent Orange, which was used in southern Vietnam, is confirmed the main source of dioxin exposure in Vietnam. Since early 1990s, agriculture of Vietnam has attained advances under intensive cultivation. Both production and yields per crop have increased significantly at the farm level, but the quant...

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Main Authors: Hoang V. Dang, Luong T. Nguyen, Ha T. Tran, Huyen T. Nguyen, Anh K. Dang, Viet D. Ly, Chiara Frazzoli
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Environmental Science
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fenvs.2017.00058/full
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author Hoang V. Dang
Luong T. Nguyen
Ha T. Tran
Huyen T. Nguyen
Anh K. Dang
Viet D. Ly
Chiara Frazzoli
author_facet Hoang V. Dang
Luong T. Nguyen
Ha T. Tran
Huyen T. Nguyen
Anh K. Dang
Viet D. Ly
Chiara Frazzoli
author_sort Hoang V. Dang
collection DOAJ
description Agent Orange, which was used in southern Vietnam, is confirmed the main source of dioxin exposure in Vietnam. Since early 1990s, agriculture of Vietnam has attained advances under intensive cultivation. Both production and yields per crop have increased significantly at the farm level, but the quantity of pesticides used in agriculture also increased in the absence of regulations and good practices. Illegal business of pesticides with false labels, as well as marketing of expired or poor quality products in stores without license are popular in Vietnam. Misuse and improper use in agriculture in Vietnam has led to a variety of problems, such as environmental pollution (including food producing animals) and adverse health impact on animals and humans. Open dumpsites worsen the general scenario. Similar to the environmental exposure, human exposure to DDT in Vietnam was ranked among the highest worldwide, with recognized effects. Exposed communities have to face birth defects, health disorders and non-communicable diseases (NCDs), from metabolic syndrome, asthma, infertility and other reproductive disorders through to diabetes, obesity, cardiovascular and neurodegenerative diseases, and cancer. A common feature of many chronic disorders and NCDs is metabolic disruption: environmental chemical factors disturb cellular homeostasis, thus affecting the ability of the body to restore a functional internal environment. Among these, endocrine disrupting pesticides can interfere with the action of hormones including metabolic hormones, and are likely to represent the main concern for developmentally-induced NCDs. Since pesticides are often persistent and bio-accumulate in the food chain through the living environment of food-producing organisms, this paper discusses relevant aspects of risk assessment, risk communication and risk management.
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spelling doaj.art-5507fe967be04fec95536d66281e6e242022-12-21T19:02:53ZengFrontiers Media S.A.Frontiers in Environmental Science2296-665X2017-09-01510.3389/fenvs.2017.00058227901Risk Factors for Non-communicable Diseases in Vietnam: A Focus on PesticidesHoang V. Dang0Luong T. Nguyen1Ha T. Tran2Huyen T. Nguyen3Anh K. Dang4Viet D. Ly5Chiara Frazzoli6Department of Biochemistry and Immunology, National Institute of Veterinary ResearchHanoi, VietnamDepartment of Biochemistry and Immunology, National Institute of Veterinary ResearchHanoi, VietnamDepartment of Biochemistry and Immunology, National Institute of Veterinary ResearchHanoi, VietnamDepartment of Biochemistry and Immunology, National Institute of Veterinary ResearchHanoi, VietnamDepartment of Biochemistry and Immunology, National Institute of Veterinary ResearchHanoi, VietnamDepartment of Biochemistry and Immunology, National Institute of Veterinary ResearchHanoi, VietnamDepartment of Cardiovascular, Dysmetabolic and Aging-Associated Diseases, Istituto Superiore di SanitàRome, ItalyAgent Orange, which was used in southern Vietnam, is confirmed the main source of dioxin exposure in Vietnam. Since early 1990s, agriculture of Vietnam has attained advances under intensive cultivation. Both production and yields per crop have increased significantly at the farm level, but the quantity of pesticides used in agriculture also increased in the absence of regulations and good practices. Illegal business of pesticides with false labels, as well as marketing of expired or poor quality products in stores without license are popular in Vietnam. Misuse and improper use in agriculture in Vietnam has led to a variety of problems, such as environmental pollution (including food producing animals) and adverse health impact on animals and humans. Open dumpsites worsen the general scenario. Similar to the environmental exposure, human exposure to DDT in Vietnam was ranked among the highest worldwide, with recognized effects. Exposed communities have to face birth defects, health disorders and non-communicable diseases (NCDs), from metabolic syndrome, asthma, infertility and other reproductive disorders through to diabetes, obesity, cardiovascular and neurodegenerative diseases, and cancer. A common feature of many chronic disorders and NCDs is metabolic disruption: environmental chemical factors disturb cellular homeostasis, thus affecting the ability of the body to restore a functional internal environment. Among these, endocrine disrupting pesticides can interfere with the action of hormones including metabolic hormones, and are likely to represent the main concern for developmentally-induced NCDs. Since pesticides are often persistent and bio-accumulate in the food chain through the living environment of food-producing organisms, this paper discusses relevant aspects of risk assessment, risk communication and risk management.http://journal.frontiersin.org/article/10.3389/fenvs.2017.00058/fullVietnampesticidesone healthexposuremetabolic syndromerisk analysis
spellingShingle Hoang V. Dang
Luong T. Nguyen
Ha T. Tran
Huyen T. Nguyen
Anh K. Dang
Viet D. Ly
Chiara Frazzoli
Risk Factors for Non-communicable Diseases in Vietnam: A Focus on Pesticides
Frontiers in Environmental Science
Vietnam
pesticides
one health
exposure
metabolic syndrome
risk analysis
title Risk Factors for Non-communicable Diseases in Vietnam: A Focus on Pesticides
title_full Risk Factors for Non-communicable Diseases in Vietnam: A Focus on Pesticides
title_fullStr Risk Factors for Non-communicable Diseases in Vietnam: A Focus on Pesticides
title_full_unstemmed Risk Factors for Non-communicable Diseases in Vietnam: A Focus on Pesticides
title_short Risk Factors for Non-communicable Diseases in Vietnam: A Focus on Pesticides
title_sort risk factors for non communicable diseases in vietnam a focus on pesticides
topic Vietnam
pesticides
one health
exposure
metabolic syndrome
risk analysis
url http://journal.frontiersin.org/article/10.3389/fenvs.2017.00058/full
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