Alterations in nucleotide-binding oligomerization domain-2 expression, pathway activation, and cytokine production in Yao syndrome

Alterations in nucleotide-binding oligomerization domain-2 expression, pathway activation, and cytokine production in Yao syndrome

Yao syndrome (YAOS) is a systemic autoinflammatory disease (SAID), formerly termed nucleotide-binding oligomerization domain-2 (NOD2)-associated autoinflammatory disease. Due to the recent identification of YAOS, the molecular mechanisms underlying its disease pathogenesis are unclear. With specific...

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Bibliographic Details
Main Authors: Christine McDonald, Min Shen, Erin E. Johnson, Amrita Kabi, Qingping Yao
Format: Article
Language:English
Published: Taylor & Francis Group 2018-02-01
Series:Autoimmunity
Subjects:
autoinflammatory disease
nod2
yao syndrome
anti-cytokine therapy
genetics
Online Access:http://dx.doi.org/10.1080/08916934.2018.1442442

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