ANALYSIS OF THE PRACTICE OF COMBINATIONAL ANTIHYPERTENSION THERAPY BY THE DATA FROM TWO OUTPATIENT REGISTRIES
Aim. To investigate on the ways antihypertension drugs (AD) prescription, including, firstly, combinational therapy, in real conditions, by the data from two outpatient registries done in district polyclinics of Ryazan city (RECVASA) and in specialized scientific center in Moscow (PROFILE).Material...
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| Format: | Article |
| Language: | Russian |
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«FIRMA «SILICEA» LLC
2017-10-01
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| Series: | Российский кардиологический журнал |
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| Online Access: | https://russjcardiol.elpub.ru/jour/article/view/2542 |
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| author | S. Yu. Martsevich A. V. Zagrebelniy Yu. V. Lukina M. M. Lukyanov A. N. Vorobyev E. A. Pravkina |
| author_facet | S. Yu. Martsevich A. V. Zagrebelniy Yu. V. Lukina M. M. Lukyanov A. N. Vorobyev E. A. Pravkina |
| author_sort | S. Yu. Martsevich |
| collection | DOAJ |
| description | Aim. To investigate on the ways antihypertension drugs (AD) prescription, including, firstly, combinational therapy, in real conditions, by the data from two outpatient registries done in district polyclinics of Ryazan city (RECVASA) and in specialized scientific center in Moscow (PROFILE).Material and methods. To the RECVAZA registry, 3690 patients were included, with cardiovascular diseases, and in 3648 (98,9%) arterial hypertension was diagnosed. Among 1531 patient’s data included into PROFILE registry during August 2011 —August 2015, hypertension was diagnosed in 1230 (80,3%). Mean age of RECVASA and PROFILE patients was 66,3±12,8 и 63,7±11,4, respectively. In overall data, males and females ratio were 28% and 72%, respectively, in RECVASA, and 54% and 46%, resp., in PROFILE.Results. In comparative analysis of the registries, it was found that RECVASA patients were older, and women predominated (72%). Hypertension was diagnosed in almost 100%, was more severe and more comorbid. By the number of prescribed AD, both registries were almost identical: every third patient was prescribed 2 drugs, every fourth — 3, every fifth was taking 1 drug. Fixed combinations of AD were used in 15%, in both registries. The target blood pressure profile was reached in 26,1% of hypertension patients in RECVASA and in 37,6% in PROFILE; in hypertension of 3rd degree — in 21,9% and 34,2% cases, respectively.Conclusion. In generally analogical approaches to AD, matching with current clinical guidelines, final result of treatment in terms of reached target blood pressure values, was significantly better in specialized cardiological center. This, probably, reflects better adherence to therapy in PROFILE patients. |
| first_indexed | 2024-04-09T20:47:43Z |
| format | Article |
| id | doaj.art-550b8b2b3c3b431dad3e6613983f96dd |
| institution | Directory Open Access Journal |
| issn | 1560-4071 2618-7620 |
| language | Russian |
| last_indexed | 2024-04-09T20:47:43Z |
| publishDate | 2017-10-01 |
| publisher | «FIRMA «SILICEA» LLC |
| record_format | Article |
| series | Российский кардиологический журнал |
| spelling | doaj.art-550b8b2b3c3b431dad3e6613983f96dd2023-03-29T21:23:28Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202017-10-010810711310.15829/1560-4071-2017-8-107-1132252ANALYSIS OF THE PRACTICE OF COMBINATIONAL ANTIHYPERTENSION THERAPY BY THE DATA FROM TWO OUTPATIENT REGISTRIESS. Yu. Martsevich0A. V. Zagrebelniy1Yu. V. Lukina2M. M. Lukyanov3A. N. Vorobyev4E. A. Pravkina5National Research Center for Preventive Medicine of the Ministry of HealthNational Research Center for Preventive Medicine of the Ministry of HealthNational Research Center for Preventive Medicine of the Ministry of HealthNational Research Center for Preventive Medicine of the Ministry of HealthRyazansky State Medical University named after I. P. PavlovRyazansky State Medical University named after I. P. PavlovAim. To investigate on the ways antihypertension drugs (AD) prescription, including, firstly, combinational therapy, in real conditions, by the data from two outpatient registries done in district polyclinics of Ryazan city (RECVASA) and in specialized scientific center in Moscow (PROFILE).Material and methods. To the RECVAZA registry, 3690 patients were included, with cardiovascular diseases, and in 3648 (98,9%) arterial hypertension was diagnosed. Among 1531 patient’s data included into PROFILE registry during August 2011 —August 2015, hypertension was diagnosed in 1230 (80,3%). Mean age of RECVASA and PROFILE patients was 66,3±12,8 и 63,7±11,4, respectively. In overall data, males and females ratio were 28% and 72%, respectively, in RECVASA, and 54% and 46%, resp., in PROFILE.Results. In comparative analysis of the registries, it was found that RECVASA patients were older, and women predominated (72%). Hypertension was diagnosed in almost 100%, was more severe and more comorbid. By the number of prescribed AD, both registries were almost identical: every third patient was prescribed 2 drugs, every fourth — 3, every fifth was taking 1 drug. Fixed combinations of AD were used in 15%, in both registries. The target blood pressure profile was reached in 26,1% of hypertension patients in RECVASA and in 37,6% in PROFILE; in hypertension of 3rd degree — in 21,9% and 34,2% cases, respectively.Conclusion. In generally analogical approaches to AD, matching with current clinical guidelines, final result of treatment in terms of reached target blood pressure values, was significantly better in specialized cardiological center. This, probably, reflects better adherence to therapy in PROFILE patients.https://russjcardiol.elpub.ru/jour/article/view/2542outpatients registriesarterial hypertensioncombination antihypertension therapyfixed combinations |
| spellingShingle | S. Yu. Martsevich A. V. Zagrebelniy Yu. V. Lukina M. M. Lukyanov A. N. Vorobyev E. A. Pravkina ANALYSIS OF THE PRACTICE OF COMBINATIONAL ANTIHYPERTENSION THERAPY BY THE DATA FROM TWO OUTPATIENT REGISTRIES Российский кардиологический журнал outpatients registries arterial hypertension combination antihypertension therapy fixed combinations |
| title | ANALYSIS OF THE PRACTICE OF COMBINATIONAL ANTIHYPERTENSION THERAPY BY THE DATA FROM TWO OUTPATIENT REGISTRIES |
| title_full | ANALYSIS OF THE PRACTICE OF COMBINATIONAL ANTIHYPERTENSION THERAPY BY THE DATA FROM TWO OUTPATIENT REGISTRIES |
| title_fullStr | ANALYSIS OF THE PRACTICE OF COMBINATIONAL ANTIHYPERTENSION THERAPY BY THE DATA FROM TWO OUTPATIENT REGISTRIES |
| title_full_unstemmed | ANALYSIS OF THE PRACTICE OF COMBINATIONAL ANTIHYPERTENSION THERAPY BY THE DATA FROM TWO OUTPATIENT REGISTRIES |
| title_short | ANALYSIS OF THE PRACTICE OF COMBINATIONAL ANTIHYPERTENSION THERAPY BY THE DATA FROM TWO OUTPATIENT REGISTRIES |
| title_sort | analysis of the practice of combinational antihypertension therapy by the data from two outpatient registries |
| topic | outpatients registries arterial hypertension combination antihypertension therapy fixed combinations |
| url | https://russjcardiol.elpub.ru/jour/article/view/2542 |
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