Tissue sampling for biliary strictures using novel elbow biopsy forceps
Abstract We aim to evaluate the safety and feasibility of novel elbow biopsy forceps with a prebent head for sampling biliary strictures in our institution. A total of 24 patients (15 males and 9 females) with biliary stricture who underwent biliary biopsy during endoscopic retrograde cholangiopancr...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2021-05-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-021-90197-4 |
| _version_ | 1818682553369886720 |
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| author | Huahui Zhang Chunyan Huo Yongxin Guo Keyuan Zhu Fengdong Li Jin Huang |
| author_facet | Huahui Zhang Chunyan Huo Yongxin Guo Keyuan Zhu Fengdong Li Jin Huang |
| author_sort | Huahui Zhang |
| collection | DOAJ |
| description | Abstract We aim to evaluate the safety and feasibility of novel elbow biopsy forceps with a prebent head for sampling biliary strictures in our institution. A total of 24 patients (15 males and 9 females) with biliary stricture who underwent biliary biopsy during endoscopic retrograde cholangiopancreatography (ERCP) using novel elbow biopsy forceps from June 2019 to August 2020 were retrospectively included. The novel biopsy forceps had a head angulation of 30 degrees and were able to cannulate the bile duct and approach the biliary strictures easily to obtain adequate samples. The technical success rate, incidence of adverse events, and consistency of pathological and surgical specimens were assessed. This device was used successfully in all patients. A total of 52 biopsy specimens were obtained from 24 patients, and all specimens could be used for histopathological examination. Seventeen patients were diagnosed with malignancy based on biopsies, and all of them underwent surgical treatment. The histopathological findings of the biopsy specimens were in accordance with the postoperative pathology diagnoses. One of the seven patients was diagnosed with a benign lesion that was proven to be malignant during surgical treatment in the follow-up period. Two patients experienced a single episode of acute pancreatitis and recovered shortly after appropriate treatment. No patients experienced biliary perforation or biliary bleeding. Biopsy using novel elbow forceps in patients with biliary stenosis is feasible and safe. The novel device and related biopsy technique may be widely applied for biliary disease differentiation. |
| first_indexed | 2024-12-17T10:20:40Z |
| format | Article |
| id | doaj.art-550bd12bf877411fb23696a23a3b08e2 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-12-17T10:20:40Z |
| publishDate | 2021-05-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-550bd12bf877411fb23696a23a3b08e22022-12-21T21:52:48ZengNature PortfolioScientific Reports2045-23222021-05-011111710.1038/s41598-021-90197-4Tissue sampling for biliary strictures using novel elbow biopsy forcepsHuahui Zhang0Chunyan Huo1Yongxin Guo2Keyuan Zhu3Fengdong Li4Jin Huang5Graduate School of Dalian Medical UniversityDepartment of Gastroenterology, Changzhou Second People’s Hospital Affiliated to Nanjing Medical UniversityGraduate School of Dalian Medical UniversityGraduate School of Dalian Medical UniversityDepartment of Gastroenterology, Changzhou Second People’s Hospital Affiliated to Nanjing Medical UniversityDepartment of Gastroenterology, Changzhou Second People’s Hospital Affiliated to Nanjing Medical UniversityAbstract We aim to evaluate the safety and feasibility of novel elbow biopsy forceps with a prebent head for sampling biliary strictures in our institution. A total of 24 patients (15 males and 9 females) with biliary stricture who underwent biliary biopsy during endoscopic retrograde cholangiopancreatography (ERCP) using novel elbow biopsy forceps from June 2019 to August 2020 were retrospectively included. The novel biopsy forceps had a head angulation of 30 degrees and were able to cannulate the bile duct and approach the biliary strictures easily to obtain adequate samples. The technical success rate, incidence of adverse events, and consistency of pathological and surgical specimens were assessed. This device was used successfully in all patients. A total of 52 biopsy specimens were obtained from 24 patients, and all specimens could be used for histopathological examination. Seventeen patients were diagnosed with malignancy based on biopsies, and all of them underwent surgical treatment. The histopathological findings of the biopsy specimens were in accordance with the postoperative pathology diagnoses. One of the seven patients was diagnosed with a benign lesion that was proven to be malignant during surgical treatment in the follow-up period. Two patients experienced a single episode of acute pancreatitis and recovered shortly after appropriate treatment. No patients experienced biliary perforation or biliary bleeding. Biopsy using novel elbow forceps in patients with biliary stenosis is feasible and safe. The novel device and related biopsy technique may be widely applied for biliary disease differentiation.https://doi.org/10.1038/s41598-021-90197-4 |
| spellingShingle | Huahui Zhang Chunyan Huo Yongxin Guo Keyuan Zhu Fengdong Li Jin Huang Tissue sampling for biliary strictures using novel elbow biopsy forceps Scientific Reports |
| title | Tissue sampling for biliary strictures using novel elbow biopsy forceps |
| title_full | Tissue sampling for biliary strictures using novel elbow biopsy forceps |
| title_fullStr | Tissue sampling for biliary strictures using novel elbow biopsy forceps |
| title_full_unstemmed | Tissue sampling for biliary strictures using novel elbow biopsy forceps |
| title_short | Tissue sampling for biliary strictures using novel elbow biopsy forceps |
| title_sort | tissue sampling for biliary strictures using novel elbow biopsy forceps |
| url | https://doi.org/10.1038/s41598-021-90197-4 |
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