Toward the Discovery of Host-Defense Peptides in Plants
Defense peptides protect multicellular eukaryotes from infections. In biomedical sciences, a dominant conceptual framework refers to defense peptides as host-defense peptides (HDPs), which are bifunctional peptides with both direct antimicrobial and immunomodulatory activities. No HDP has been repor...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2020-08-01
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| Series: | Frontiers in Immunology |
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| Online Access: | https://www.frontiersin.org/article/10.3389/fimmu.2020.01825/full |
| _version_ | 1828825706349461504 |
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| author | Benjamin Petre |
| author_facet | Benjamin Petre |
| author_sort | Benjamin Petre |
| collection | DOAJ |
| description | Defense peptides protect multicellular eukaryotes from infections. In biomedical sciences, a dominant conceptual framework refers to defense peptides as host-defense peptides (HDPs), which are bifunctional peptides with both direct antimicrobial and immunomodulatory activities. No HDP has been reported in plants so far, and the very concept of HDP has not been captured yet by the plant science community. Plant science thus lacks the conceptual framework that would coordinate research efforts aimed at discovering plant HDPs. In this perspective article, I used bibliometric and literature survey approaches to raise awareness about the HDP concept among plant scientists, and to encourage research efforts aimed at discovering plant HDPs. Such discovery would enrich our comprehension of the function and evolution of the plant immune system, and provide us with novel molecular tools to develop innovative strategies to control crop diseases. |
| first_indexed | 2024-12-12T14:24:02Z |
| format | Article |
| id | doaj.art-550cdcdc2fab46d9b58adae080c9ed44 |
| institution | Directory Open Access Journal |
| issn | 1664-3224 |
| language | English |
| last_indexed | 2024-12-12T14:24:02Z |
| publishDate | 2020-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Immunology |
| spelling | doaj.art-550cdcdc2fab46d9b58adae080c9ed442022-12-22T00:21:44ZengFrontiers Media S.A.Frontiers in Immunology1664-32242020-08-011110.3389/fimmu.2020.01825557828Toward the Discovery of Host-Defense Peptides in PlantsBenjamin PetreDefense peptides protect multicellular eukaryotes from infections. In biomedical sciences, a dominant conceptual framework refers to defense peptides as host-defense peptides (HDPs), which are bifunctional peptides with both direct antimicrobial and immunomodulatory activities. No HDP has been reported in plants so far, and the very concept of HDP has not been captured yet by the plant science community. Plant science thus lacks the conceptual framework that would coordinate research efforts aimed at discovering plant HDPs. In this perspective article, I used bibliometric and literature survey approaches to raise awareness about the HDP concept among plant scientists, and to encourage research efforts aimed at discovering plant HDPs. Such discovery would enrich our comprehension of the function and evolution of the plant immune system, and provide us with novel molecular tools to develop innovative strategies to control crop diseases.https://www.frontiersin.org/article/10.3389/fimmu.2020.01825/fullantimicrobial peptidespeptide elicitorsconcept transferplant immunitydefensinsthaumatin-like proteins |
| spellingShingle | Benjamin Petre Toward the Discovery of Host-Defense Peptides in Plants Frontiers in Immunology antimicrobial peptides peptide elicitors concept transfer plant immunity defensins thaumatin-like proteins |
| title | Toward the Discovery of Host-Defense Peptides in Plants |
| title_full | Toward the Discovery of Host-Defense Peptides in Plants |
| title_fullStr | Toward the Discovery of Host-Defense Peptides in Plants |
| title_full_unstemmed | Toward the Discovery of Host-Defense Peptides in Plants |
| title_short | Toward the Discovery of Host-Defense Peptides in Plants |
| title_sort | toward the discovery of host defense peptides in plants |
| topic | antimicrobial peptides peptide elicitors concept transfer plant immunity defensins thaumatin-like proteins |
| url | https://www.frontiersin.org/article/10.3389/fimmu.2020.01825/full |
| work_keys_str_mv | AT benjaminpetre towardthediscoveryofhostdefensepeptidesinplants |