Global Analysis and Optimal Control of a Periodic Visceral Leishmaniasis Model
In this paper, we propose and analyze a mathematical model for the dynamics of visceral leishmaniasis with seasonality. Our results show that the disease-free equilibrium is globally asymptotically stable under certain conditions when R 0 , the basic reproduction number, is less than unity. W...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2017-12-01
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Series: | Mathematics |
Subjects: | |
Online Access: | https://www.mdpi.com/2227-7390/5/4/80 |
Summary: | In this paper, we propose and analyze a mathematical model for the dynamics of visceral leishmaniasis with seasonality. Our results show that the disease-free equilibrium is globally asymptotically stable under certain conditions when R 0 , the basic reproduction number, is less than unity. When R 0 > 1 and under some conditions, then our system has a unique positive ω -periodic solution that is globally asymptotically stable. Applying two controls, vaccination and treatment, to our model forces the system to be non-periodic, and all fractions of infected populations settle on a very low level. |
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ISSN: | 2227-7390 |