Repurposing and computational design of PARP inhibitors as SARS-CoV-2 inhibitors

Repurposing and computational design of PARP inhibitors as SARS-CoV-2 inhibitors

Abstract Coronavirus disease 2019 (COVID-19) is a recent pandemic that caused serious global emergency. To identify new and effective therapeutics, we employed a drug repurposing approach. The poly (ADP ribose) polymerase inhibitors were used for this purpose and were repurposed against the main pro...

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Bibliografiske detaljer
Main Authors:	Shailima Rampogu, Tae Sung Jung, Min Woo Ha, Keun Woo Lee
Format:	Article
Sprog:	English
Udgivet:	Nature Portfolio 2023-06-01
Serier:	Scientific Reports
Online adgang:	https://doi.org/10.1038/s41598-023-36342-7

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