Repurposing and computational design of PARP inhibitors as SARS-CoV-2 inhibitors

Abstract Coronavirus disease 2019 (COVID-19) is a recent pandemic that caused serious global emergency. To identify new and effective therapeutics, we employed a drug repurposing approach. The poly (ADP ribose) polymerase inhibitors were used for this purpose and were repurposed against the main pro...

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Detalles Bibliográficos
Main Authors: Shailima Rampogu, Tae Sung Jung, Min Woo Ha, Keun Woo Lee
Formato: Artigo
Idioma:English
Publicado: Nature Portfolio 2023-06-01
Series:Scientific Reports
Acceso en liña:https://doi.org/10.1038/s41598-023-36342-7