Repurposing and computational design of PARP inhibitors as SARS-CoV-2 inhibitors

Abstract Coronavirus disease 2019 (COVID-19) is a recent pandemic that caused serious global emergency. To identify new and effective therapeutics, we employed a drug repurposing approach. The poly (ADP ribose) polymerase inhibitors were used for this purpose and were repurposed against the main pro...

Полное описание

Библиографические подробности
Главные авторы: Shailima Rampogu, Tae Sung Jung, Min Woo Ha, Keun Woo Lee
Формат: Статья
Язык:English
Опубликовано: Nature Portfolio 2023-06-01
Серии:Scientific Reports
Online-ссылка:https://doi.org/10.1038/s41598-023-36342-7