Development of a Multivariate Predictive Dissolution Model for Tablets Coated with Cellulose Ester Blends

Development of a Multivariate Predictive Dissolution Model for Tablets Coated with Cellulose Ester Blends

The focus of the present investigation was to develop a predictive dissolution model for tablets coated with blends of cellulose acetate butyrate (CAB) 171-15 and cellulose acetate phthalate (C-A-P) using the design of experiment and chemometric approaches. Diclofenac sodium was used as a model drug...

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Bibliographic Details
Main Authors: Eman M. Mohamed, Tahir Khuroo, Hamideh Afrooz, Sathish Dharani, Khaldia Sediri, Phillip Cook, Rajendran Arunagiri, Mansoor A. Khan, Ziyaur Rahman
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Pharmaceuticals
Subjects:
cellulose acetate butyrate
cellaburate
diclofenac
dissolution
hyperspectroscopy
multivariate
Online Access:https://www.mdpi.com/1424-8247/13/10/311

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