Hydrogen-generating Si-based agent protects against skin flap ischemia–reperfusion injury in rats
Abstract Hydrogen is effective against ischemia–reperfusion (I/R) injury in skin flaps. However, the difficulty of continuously administering a sufficient amount of hydrogen using conventional methods has been an issue in the clinical application of hydrogen-based therapy. An Si-based agent administ...
Main Authors: | Naoya Otani, Koichi Tomita, Yuki Kobayashi, Kazuya Kuroda, Yoshihisa Koyama, Hikaru Kobayashi, Tateki Kubo |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-04-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-022-10228-6 |
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