The Mycobacteriophage Ms6 LysB <i>N</i>-Terminus Displays Peptidoglycan Binding Affinity

The Mycobacteriophage Ms6 LysB <i>N</i>-Terminus Displays Peptidoglycan Binding Affinity

Double-stranded DNA bacteriophages end their lytic cycle by disrupting the host cell envelope, which allows the release of the virion progeny. Each phage must synthesize lysis proteins that target each cell barrier to phage release. In addition to holins, which permeabilize the cytoplasmic membrane,...

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Bibliographic Details
Main Authors: Adriano M. Gigante, Francisco Olivença, Maria João Catalão, Paula Leandro, José Moniz-Pereira, Sérgio R. Filipe, Madalena Pimentel
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Viruses
Subjects:
mycobacteriophage Ms6
LysB
phage lysis
mycobacteria
peptidoglycan binding
Online Access:https://www.mdpi.com/1999-4915/13/7/1377

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