Sickle cell trait: not as benign as once thought

We describe a case of renal papillary necrosis in a middle-aged female with sickle cell trait who presented with gross hematuria. We wish to highlight this case for several reasons. Sickle cell trait is often viewed as a benign condition despite the fact that it is associated with significant morbid...

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Main Authors: Uqba Khan, Lauren Kleess, Justin Yeh, Charles Berko, Sapna Kuehl
Format: Article
Language:English
Published: Greater Baltimore Medical Center 2014-11-01
Series:Journal of Community Hospital Internal Medicine Perspectives
Subjects:
Online Access:http://www.jchimp.net/index.php/jchimp/article/download/25418/pdf_1
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author Uqba Khan
Lauren Kleess
Justin Yeh
Charles Berko
Sapna Kuehl
author_facet Uqba Khan
Lauren Kleess
Justin Yeh
Charles Berko
Sapna Kuehl
author_sort Uqba Khan
collection DOAJ
description We describe a case of renal papillary necrosis in a middle-aged female with sickle cell trait who presented with gross hematuria. We wish to highlight this case for several reasons. Sickle cell trait is often viewed as a benign condition despite the fact that it is associated with significant morbidity such as renal papillary necrosis and renal medullary carcinoma. Appropriate evaluation needs to be undertaken to promptly diagnose renal papillary necrosis and differentiate it from renal medullary carcinoma as this can result in deadly consequences for patients. CT urography has emerged as a diagnostic study to evaluate hematuria in such patients. We review the pathophysiology, diagnosis, and management of renal papillary necrosis in patients with sickle cell trait.
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spelling doaj.art-55201baee02e4cb4aa40d465dda737a12023-01-02T22:22:47ZengGreater Baltimore Medical CenterJournal of Community Hospital Internal Medicine Perspectives2000-96662014-11-01451310.3402/jchimp.v4.2541825418Sickle cell trait: not as benign as once thoughtUqba Khan0Lauren Kleess1Justin Yeh2Charles Berko3Sapna Kuehl4Department of Internal Medicine, Saint Agnes Hospital Baltimore, Baltimore, MD, USADepartment of Internal Medicine, Saint Agnes Hospital Baltimore, Baltimore, MD, USADepartment of Internal Medicine, Saint Agnes Hospital Baltimore, Baltimore, MD, USADepartment of Internal Medicine, Saint Agnes Hospital Baltimore, Baltimore, MD, USADepartment of Internal Medicine, Saint Agnes Hospital Baltimore, Baltimore, MD, USAWe describe a case of renal papillary necrosis in a middle-aged female with sickle cell trait who presented with gross hematuria. We wish to highlight this case for several reasons. Sickle cell trait is often viewed as a benign condition despite the fact that it is associated with significant morbidity such as renal papillary necrosis and renal medullary carcinoma. Appropriate evaluation needs to be undertaken to promptly diagnose renal papillary necrosis and differentiate it from renal medullary carcinoma as this can result in deadly consequences for patients. CT urography has emerged as a diagnostic study to evaluate hematuria in such patients. We review the pathophysiology, diagnosis, and management of renal papillary necrosis in patients with sickle cell trait.http://www.jchimp.net/index.php/jchimp/article/download/25418/pdf_1Sickle cell traitrenal papillary necrosisCT urography
spellingShingle Uqba Khan
Lauren Kleess
Justin Yeh
Charles Berko
Sapna Kuehl
Sickle cell trait: not as benign as once thought
Journal of Community Hospital Internal Medicine Perspectives
Sickle cell trait
renal papillary necrosis
CT urography
title Sickle cell trait: not as benign as once thought
title_full Sickle cell trait: not as benign as once thought
title_fullStr Sickle cell trait: not as benign as once thought
title_full_unstemmed Sickle cell trait: not as benign as once thought
title_short Sickle cell trait: not as benign as once thought
title_sort sickle cell trait not as benign as once thought
topic Sickle cell trait
renal papillary necrosis
CT urography
url http://www.jchimp.net/index.php/jchimp/article/download/25418/pdf_1
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