Sickle cell trait: not as benign as once thought
We describe a case of renal papillary necrosis in a middle-aged female with sickle cell trait who presented with gross hematuria. We wish to highlight this case for several reasons. Sickle cell trait is often viewed as a benign condition despite the fact that it is associated with significant morbid...
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Format: | Article |
Language: | English |
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Greater Baltimore Medical Center
2014-11-01
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Series: | Journal of Community Hospital Internal Medicine Perspectives |
Subjects: | |
Online Access: | http://www.jchimp.net/index.php/jchimp/article/download/25418/pdf_1 |
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author | Uqba Khan Lauren Kleess Justin Yeh Charles Berko Sapna Kuehl |
author_facet | Uqba Khan Lauren Kleess Justin Yeh Charles Berko Sapna Kuehl |
author_sort | Uqba Khan |
collection | DOAJ |
description | We describe a case of renal papillary necrosis in a middle-aged female with sickle cell trait who presented with gross hematuria. We wish to highlight this case for several reasons. Sickle cell trait is often viewed as a benign condition despite the fact that it is associated with significant morbidity such as renal papillary necrosis and renal medullary carcinoma. Appropriate evaluation needs to be undertaken to promptly diagnose renal papillary necrosis and differentiate it from renal medullary carcinoma as this can result in deadly consequences for patients. CT urography has emerged as a diagnostic study to evaluate hematuria in such patients. We review the pathophysiology, diagnosis, and management of renal papillary necrosis in patients with sickle cell trait. |
first_indexed | 2024-04-11T02:27:58Z |
format | Article |
id | doaj.art-55201baee02e4cb4aa40d465dda737a1 |
institution | Directory Open Access Journal |
issn | 2000-9666 |
language | English |
last_indexed | 2024-04-11T02:27:58Z |
publishDate | 2014-11-01 |
publisher | Greater Baltimore Medical Center |
record_format | Article |
series | Journal of Community Hospital Internal Medicine Perspectives |
spelling | doaj.art-55201baee02e4cb4aa40d465dda737a12023-01-02T22:22:47ZengGreater Baltimore Medical CenterJournal of Community Hospital Internal Medicine Perspectives2000-96662014-11-01451310.3402/jchimp.v4.2541825418Sickle cell trait: not as benign as once thoughtUqba Khan0Lauren Kleess1Justin Yeh2Charles Berko3Sapna Kuehl4Department of Internal Medicine, Saint Agnes Hospital Baltimore, Baltimore, MD, USADepartment of Internal Medicine, Saint Agnes Hospital Baltimore, Baltimore, MD, USADepartment of Internal Medicine, Saint Agnes Hospital Baltimore, Baltimore, MD, USADepartment of Internal Medicine, Saint Agnes Hospital Baltimore, Baltimore, MD, USADepartment of Internal Medicine, Saint Agnes Hospital Baltimore, Baltimore, MD, USAWe describe a case of renal papillary necrosis in a middle-aged female with sickle cell trait who presented with gross hematuria. We wish to highlight this case for several reasons. Sickle cell trait is often viewed as a benign condition despite the fact that it is associated with significant morbidity such as renal papillary necrosis and renal medullary carcinoma. Appropriate evaluation needs to be undertaken to promptly diagnose renal papillary necrosis and differentiate it from renal medullary carcinoma as this can result in deadly consequences for patients. CT urography has emerged as a diagnostic study to evaluate hematuria in such patients. We review the pathophysiology, diagnosis, and management of renal papillary necrosis in patients with sickle cell trait.http://www.jchimp.net/index.php/jchimp/article/download/25418/pdf_1Sickle cell traitrenal papillary necrosisCT urography |
spellingShingle | Uqba Khan Lauren Kleess Justin Yeh Charles Berko Sapna Kuehl Sickle cell trait: not as benign as once thought Journal of Community Hospital Internal Medicine Perspectives Sickle cell trait renal papillary necrosis CT urography |
title | Sickle cell trait: not as benign as once thought |
title_full | Sickle cell trait: not as benign as once thought |
title_fullStr | Sickle cell trait: not as benign as once thought |
title_full_unstemmed | Sickle cell trait: not as benign as once thought |
title_short | Sickle cell trait: not as benign as once thought |
title_sort | sickle cell trait not as benign as once thought |
topic | Sickle cell trait renal papillary necrosis CT urography |
url | http://www.jchimp.net/index.php/jchimp/article/download/25418/pdf_1 |
work_keys_str_mv | AT uqbakhan sicklecelltraitnotasbenignasoncethought AT laurenkleess sicklecelltraitnotasbenignasoncethought AT justinyeh sicklecelltraitnotasbenignasoncethought AT charlesberko sicklecelltraitnotasbenignasoncethought AT sapnakuehl sicklecelltraitnotasbenignasoncethought |