Nanoparticles Obtained from Zein for Encapsulation of Mesalazine

Nanoparticles Obtained from Zein for Encapsulation of Mesalazine

We encapsulated MSZ in zein nanoparticles (NP-ZN) using a desolvation method followed by drying in a mini spray dryer. These nanoparticles exhibited a size of 266.6 ± 52 nm, IPD of 0.14 ± 1.1 and zeta potential of −36.4 ± 1.5 mV, suggesting colloidal stability. Quantification using HPLC showed a dru...

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Bibliographic Details
Main Authors: Izabela Borges C. Lima, Lina Clara G. A. I. Moreno, Ana Victória Peres, Ana Cristina Gramoza Santana, Adonias Carvalho, Mariana H. Chaves, Lorena Lima, Rayran Walter Sousa, Dalton Dittz, Hercília M. L. Rolim, Lívio César Cunha Nunes
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Pharmaceutics
Subjects:
natural polymer
zein
5-ASA
nanoparticles
colon
Online Access:https://www.mdpi.com/1999-4923/14/12/2830

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