Adenosquamous Carcinoma of the Colon: A Report of Two Cases and Literature Review
Colon cancer is one of the commonest tumours in the world. Although most colon cancer patients are colonized by adenocarcinoma, some other pathologies such as adenosquamous carcinoma are rarely encountered. We present two patients with right colon adenosquamous carcinoma. Both patients were males an...
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Format: | Article |
Language: | English |
Published: |
Shiraz University of Medical Sciences
2023-04-01
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Series: | Middle East Journal of Cancer |
Subjects: | |
Online Access: | https://mejc.sums.ac.ir/article_48505_7cb72e86acdc6b4a4b6751a2b296e716.pdf |
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author | Mohammad Zuhdy Reham Alghandour Mohamed Elhawary Islam Metwally Farida Shokeir |
author_facet | Mohammad Zuhdy Reham Alghandour Mohamed Elhawary Islam Metwally Farida Shokeir |
author_sort | Mohammad Zuhdy |
collection | DOAJ |
description | Colon cancer is one of the commonest tumours in the world. Although most colon cancer patients are colonized by adenocarcinoma, some other pathologies such as adenosquamous carcinoma are rarely encountered. We present two patients with right colon adenosquamous carcinoma. Both patients were males and both suffered a nodepositive disease. Furthermore, one of them developed recurrence 7 months after initial radical surgery, despite formal colon adjuvant chemotherapy given. In conclusion, the patients with adenosquamous colon cancer are a subgroup with a worse prognosis, and questionable response to the conventional chemotherapeutic regimens as FOLFOX (flourouracil, leucoverin, and oxaloplatin) and CAPEOX (capecitabine and oxaloplatin). |
first_indexed | 2024-04-09T17:50:19Z |
format | Article |
id | doaj.art-55221f1d8ac24cceba0a7015de97b5ac |
institution | Directory Open Access Journal |
issn | 2008-6709 2008-6687 |
language | English |
last_indexed | 2024-04-09T17:50:19Z |
publishDate | 2023-04-01 |
publisher | Shiraz University of Medical Sciences |
record_format | Article |
series | Middle East Journal of Cancer |
spelling | doaj.art-55221f1d8ac24cceba0a7015de97b5ac2023-04-16T08:23:55ZengShiraz University of Medical SciencesMiddle East Journal of Cancer2008-67092008-66872023-04-0114232733110.30476/mejc.2022.92185.164848505Adenosquamous Carcinoma of the Colon: A Report of Two Cases and Literature ReviewMohammad Zuhdy0Reham Alghandour1Mohamed Elhawary2Islam Metwally3Farida Shokeir4Surgical Oncology Department, Oncology Center Mansoura University (OCMU), Mansoura, EgyptMedical Oncology Department, Oncology Center Mansoura University (OCMU), Mansoura, EgyptRadiology Department, Mansoura University Hospitals (MUH), Mansoura, EgyptSurgical Oncology Department, Oncology Center Mansoura University (OCMU), Mansoura, EgyptPathology Department, Mansoura University Hospitals (MUH), Mansoura, EgyptColon cancer is one of the commonest tumours in the world. Although most colon cancer patients are colonized by adenocarcinoma, some other pathologies such as adenosquamous carcinoma are rarely encountered. We present two patients with right colon adenosquamous carcinoma. Both patients were males and both suffered a nodepositive disease. Furthermore, one of them developed recurrence 7 months after initial radical surgery, despite formal colon adjuvant chemotherapy given. In conclusion, the patients with adenosquamous colon cancer are a subgroup with a worse prognosis, and questionable response to the conventional chemotherapeutic regimens as FOLFOX (flourouracil, leucoverin, and oxaloplatin) and CAPEOX (capecitabine and oxaloplatin).https://mejc.sums.ac.ir/article_48505_7cb72e86acdc6b4a4b6751a2b296e716.pdfcarcinomaadenosquamouscolon neoplasms |
spellingShingle | Mohammad Zuhdy Reham Alghandour Mohamed Elhawary Islam Metwally Farida Shokeir Adenosquamous Carcinoma of the Colon: A Report of Two Cases and Literature Review Middle East Journal of Cancer carcinoma adenosquamous colon neoplasms |
title | Adenosquamous Carcinoma of the Colon: A Report of Two Cases and Literature Review |
title_full | Adenosquamous Carcinoma of the Colon: A Report of Two Cases and Literature Review |
title_fullStr | Adenosquamous Carcinoma of the Colon: A Report of Two Cases and Literature Review |
title_full_unstemmed | Adenosquamous Carcinoma of the Colon: A Report of Two Cases and Literature Review |
title_short | Adenosquamous Carcinoma of the Colon: A Report of Two Cases and Literature Review |
title_sort | adenosquamous carcinoma of the colon a report of two cases and literature review |
topic | carcinoma adenosquamous colon neoplasms |
url | https://mejc.sums.ac.ir/article_48505_7cb72e86acdc6b4a4b6751a2b296e716.pdf |
work_keys_str_mv | AT mohammadzuhdy adenosquamouscarcinomaofthecolonareportoftwocasesandliteraturereview AT rehamalghandour adenosquamouscarcinomaofthecolonareportoftwocasesandliteraturereview AT mohamedelhawary adenosquamouscarcinomaofthecolonareportoftwocasesandliteraturereview AT islammetwally adenosquamouscarcinomaofthecolonareportoftwocasesandliteraturereview AT faridashokeir adenosquamouscarcinomaofthecolonareportoftwocasesandliteraturereview |