Adenosquamous Carcinoma of the Colon: A Report of Two Cases and Literature Review

Colon cancer is one of the commonest tumours in the world. Although most colon cancer patients are colonized by adenocarcinoma, some other pathologies such as adenosquamous carcinoma are rarely encountered. We present two patients with right colon adenosquamous carcinoma. Both patients were males an...

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Main Authors: Mohammad Zuhdy, Reham Alghandour, Mohamed Elhawary, Islam Metwally, Farida Shokeir
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2023-04-01
Series:Middle East Journal of Cancer
Subjects:
Online Access:https://mejc.sums.ac.ir/article_48505_7cb72e86acdc6b4a4b6751a2b296e716.pdf
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author Mohammad Zuhdy
Reham Alghandour
Mohamed Elhawary
Islam Metwally
Farida Shokeir
author_facet Mohammad Zuhdy
Reham Alghandour
Mohamed Elhawary
Islam Metwally
Farida Shokeir
author_sort Mohammad Zuhdy
collection DOAJ
description Colon cancer is one of the commonest tumours in the world. Although most colon cancer patients are colonized by adenocarcinoma, some other pathologies such as adenosquamous carcinoma are rarely encountered. We present two patients with right colon adenosquamous carcinoma. Both patients were males and both suffered a nodepositive disease. Furthermore, one of them developed recurrence 7 months after initial radical surgery, despite formal colon adjuvant chemotherapy given. In conclusion, the patients with adenosquamous colon cancer are a subgroup with a worse prognosis, and questionable response to the conventional chemotherapeutic regimens as FOLFOX (flourouracil, leucoverin, and oxaloplatin) and CAPEOX (capecitabine and oxaloplatin).
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spelling doaj.art-55221f1d8ac24cceba0a7015de97b5ac2023-04-16T08:23:55ZengShiraz University of Medical SciencesMiddle East Journal of Cancer2008-67092008-66872023-04-0114232733110.30476/mejc.2022.92185.164848505Adenosquamous Carcinoma of the Colon: A Report of Two Cases and Literature ReviewMohammad Zuhdy0Reham Alghandour1Mohamed Elhawary2Islam Metwally3Farida Shokeir4Surgical Oncology Department, Oncology Center Mansoura University (OCMU), Mansoura, EgyptMedical Oncology Department, Oncology Center Mansoura University (OCMU), Mansoura, EgyptRadiology Department, Mansoura University Hospitals (MUH), Mansoura, EgyptSurgical Oncology Department, Oncology Center Mansoura University (OCMU), Mansoura, EgyptPathology Department, Mansoura University Hospitals (MUH), Mansoura, EgyptColon cancer is one of the commonest tumours in the world. Although most colon cancer patients are colonized by adenocarcinoma, some other pathologies such as adenosquamous carcinoma are rarely encountered. We present two patients with right colon adenosquamous carcinoma. Both patients were males and both suffered a nodepositive disease. Furthermore, one of them developed recurrence 7 months after initial radical surgery, despite formal colon adjuvant chemotherapy given. In conclusion, the patients with adenosquamous colon cancer are a subgroup with a worse prognosis, and questionable response to the conventional chemotherapeutic regimens as FOLFOX (flourouracil, leucoverin, and oxaloplatin) and CAPEOX (capecitabine and oxaloplatin).https://mejc.sums.ac.ir/article_48505_7cb72e86acdc6b4a4b6751a2b296e716.pdfcarcinomaadenosquamouscolon neoplasms
spellingShingle Mohammad Zuhdy
Reham Alghandour
Mohamed Elhawary
Islam Metwally
Farida Shokeir
Adenosquamous Carcinoma of the Colon: A Report of Two Cases and Literature Review
Middle East Journal of Cancer
carcinoma
adenosquamous
colon neoplasms
title Adenosquamous Carcinoma of the Colon: A Report of Two Cases and Literature Review
title_full Adenosquamous Carcinoma of the Colon: A Report of Two Cases and Literature Review
title_fullStr Adenosquamous Carcinoma of the Colon: A Report of Two Cases and Literature Review
title_full_unstemmed Adenosquamous Carcinoma of the Colon: A Report of Two Cases and Literature Review
title_short Adenosquamous Carcinoma of the Colon: A Report of Two Cases and Literature Review
title_sort adenosquamous carcinoma of the colon a report of two cases and literature review
topic carcinoma
adenosquamous
colon neoplasms
url https://mejc.sums.ac.ir/article_48505_7cb72e86acdc6b4a4b6751a2b296e716.pdf
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AT rehamalghandour adenosquamouscarcinomaofthecolonareportoftwocasesandliteraturereview
AT mohamedelhawary adenosquamouscarcinomaofthecolonareportoftwocasesandliteraturereview
AT islammetwally adenosquamouscarcinomaofthecolonareportoftwocasesandliteraturereview
AT faridashokeir adenosquamouscarcinomaofthecolonareportoftwocasesandliteraturereview