A Novel Approach for Position Verification and Dose Calculation through Local MVCT Reconstruction

Traditional positioning verification using cone-beam computed tomography (CBCT) may incur errors due to potential misalignments between the isocenter of CBCT and the treatment beams in radiotherapy. This study introduces an innovative method for verifying patient positioning in radiotherapy. Initial...

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Main Authors: Jun Zhang, Zerui Chen, Yuxin Lei, Junhai Wen
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Diagnostics
Subjects:
Online Access:https://www.mdpi.com/2075-4418/14/5/482
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author Jun Zhang
Zerui Chen
Yuxin Lei
Junhai Wen
author_facet Jun Zhang
Zerui Chen
Yuxin Lei
Junhai Wen
author_sort Jun Zhang
collection DOAJ
description Traditional positioning verification using cone-beam computed tomography (CBCT) may incur errors due to potential misalignments between the isocenter of CBCT and the treatment beams in radiotherapy. This study introduces an innovative method for verifying patient positioning in radiotherapy. Initially, the transmission images from an electronic portal imaging device (EPID) are acquired from 10 distinct angles. Utilizing the ART-TV algorithm, a sparse reconstruction of local megavoltage computed tomography (MVCT) is performed. Subsequently, this MVCT is aligned with the planning CT via a three-dimensional mutual information registration technique, pinpointing any patient-positioning discrepancies and facilitating corrective adjustments to the treatment setup. Notably, this approach employs the same radiation source as used in treatment to obtain three-dimensional images, thereby circumventing errors stemming from misalignment between the isocenter of CBCT and the accelerator. The registration process requires only 10 EPID images, and the dose absorbed during this process is included in the total dose calculation. The results show that our method’s reconstructed MVCT images fulfill the requirements for registration, and the registration algorithm accurately detects positioning errors, thus allowing for adjustments in the patient’s treatment position and precise calculation of the absorbed dose.
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spelling doaj.art-5526a4575a4041709685bce68edf93082024-03-12T16:41:55ZengMDPI AGDiagnostics2075-44182024-02-0114548210.3390/diagnostics14050482A Novel Approach for Position Verification and Dose Calculation through Local MVCT ReconstructionJun Zhang0Zerui Chen1Yuxin Lei2Junhai Wen3College of Computer Science and Technology, Taiyuan University of Technology, Taiyuan 030024, ChinaSchool of Life Science, Beijing Institute of Technology, Beijing 100081, ChinaSchool of Life Science, Beijing Institute of Technology, Beijing 100081, ChinaSchool of Life Science, Beijing Institute of Technology, Beijing 100081, ChinaTraditional positioning verification using cone-beam computed tomography (CBCT) may incur errors due to potential misalignments between the isocenter of CBCT and the treatment beams in radiotherapy. This study introduces an innovative method for verifying patient positioning in radiotherapy. Initially, the transmission images from an electronic portal imaging device (EPID) are acquired from 10 distinct angles. Utilizing the ART-TV algorithm, a sparse reconstruction of local megavoltage computed tomography (MVCT) is performed. Subsequently, this MVCT is aligned with the planning CT via a three-dimensional mutual information registration technique, pinpointing any patient-positioning discrepancies and facilitating corrective adjustments to the treatment setup. Notably, this approach employs the same radiation source as used in treatment to obtain three-dimensional images, thereby circumventing errors stemming from misalignment between the isocenter of CBCT and the accelerator. The registration process requires only 10 EPID images, and the dose absorbed during this process is included in the total dose calculation. The results show that our method’s reconstructed MVCT images fulfill the requirements for registration, and the registration algorithm accurately detects positioning errors, thus allowing for adjustments in the patient’s treatment position and precise calculation of the absorbed dose.https://www.mdpi.com/2075-4418/14/5/482EPIDMVCTdose calculationpositioning verificationregistration
spellingShingle Jun Zhang
Zerui Chen
Yuxin Lei
Junhai Wen
A Novel Approach for Position Verification and Dose Calculation through Local MVCT Reconstruction
Diagnostics
EPID
MVCT
dose calculation
positioning verification
registration
title A Novel Approach for Position Verification and Dose Calculation through Local MVCT Reconstruction
title_full A Novel Approach for Position Verification and Dose Calculation through Local MVCT Reconstruction
title_fullStr A Novel Approach for Position Verification and Dose Calculation through Local MVCT Reconstruction
title_full_unstemmed A Novel Approach for Position Verification and Dose Calculation through Local MVCT Reconstruction
title_short A Novel Approach for Position Verification and Dose Calculation through Local MVCT Reconstruction
title_sort novel approach for position verification and dose calculation through local mvct reconstruction
topic EPID
MVCT
dose calculation
positioning verification
registration
url https://www.mdpi.com/2075-4418/14/5/482
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