Resveratrol inhibits LPS-induced apoptosis in VSC4.1 motoneurons through enhancing SIRT1-mediated autophagy

Resveratrol inhibits LPS-induced apoptosis in VSC4.1 motoneurons through enhancing SIRT1-mediated autophagy

Objective(s): Resveratrol has been recognized as a potential therapeutic drug in spinal cord injury (SCI). Sirtuin 1 (SIRT1) is vital in the regulation of apoptosis and cell stress response. In this research, our purpose was to explore the mechanisms of resveratrol on neuroprotection and to explore...

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Bibliographic Details
Main Authors: He Tian, Haosen Zhao, XIfan Mei, Daoyong Li, Jiaquan Lin, Sen Lin, Changwei Song
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2021-01-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
apoptosis
autophagy
lipopolysaccharide
resveratrol
sirtuin 1
spinal cord injury
Online Access:https://ijbms.mums.ac.ir/article_17052_b668bf17bd2c14841d9584c6d5b69cd3.pdf

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