Echocardiographic assessment of right ventricular dysfunction and outcome in patients with severe Covid-19 Pneumonia
ABSTRACTBackground Fatal cardiovascular complications and acute respiratory distress syndrome (ARDS) account for the majority of SARS-CoV-2-associated deaths. The objective of this research was to find transthoracic echocardiography (TTE) of right ventricular (RV) dysfunction parameters that can be...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2023-12-01
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| Series: | Egyptian Journal of Anaesthesia |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/11101849.2023.2204576 |
| _version_ | 1797840270465695744 |
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| author | Ali Salam Tayseer Zaytoun Tamer Abdallah Dina Zidan |
| author_facet | Ali Salam Tayseer Zaytoun Tamer Abdallah Dina Zidan |
| author_sort | Ali Salam |
| collection | DOAJ |
| description | ABSTRACTBackground Fatal cardiovascular complications and acute respiratory distress syndrome (ARDS) account for the majority of SARS-CoV-2-associated deaths. The objective of this research was to find transthoracic echocardiography (TTE) of right ventricular (RV) dysfunction parameters that can be utilized to predict outcomes in individuals with severe COVID-19 pneumonia;Methods This observational research included 90 cases with severe COVID-19 pneumonia subjected to TTE on the day of admission and 3rd day to determine the relationship between severity, mortality in severe COVID-19 pneumonia and RV function parameters;Results TAPSE, SPAP, RVD, RV-WT, and RV-FAC had significant differences among the two groups. PaO2/FiO2 and average MAP were significantly correlated with all RV parameters. Adjusted multivariate regression analysis on day 1 showed that TAPSE and SPAP followed by RVFAC were significantly related to mortality. While on day 3, it was revealed that RVFAC then SPAP were significantly related to mortality. SPAP, with a cutoff point >46 mmHg, was the most sensitive parameter, while the most specific to predict mortality was TAPSE, with a cutoff point ≤15 mm.Conclusions In cases with severe COVID-19 pneumonia, prediction of mortality can be performed by measuring RV parameters by TTE with high sensitivity and specificity. |
| first_indexed | 2024-04-09T16:12:12Z |
| format | Article |
| id | doaj.art-552cdf9999a545a182e08a569ae60274 |
| institution | Directory Open Access Journal |
| issn | 1110-1849 |
| language | English |
| last_indexed | 2024-04-09T16:12:12Z |
| publishDate | 2023-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Egyptian Journal of Anaesthesia |
| spelling | doaj.art-552cdf9999a545a182e08a569ae602742023-04-24T08:55:50ZengTaylor & Francis GroupEgyptian Journal of Anaesthesia1110-18492023-12-0139137738310.1080/11101849.2023.2204576Echocardiographic assessment of right ventricular dysfunction and outcome in patients with severe Covid-19 PneumoniaAli Salam0Tayseer Zaytoun1Tamer Abdallah2Dina Zidan3Department of Critical Care Medicine, Faculty of Medicine, Alexandria University EgyptCritical Care Medicine, Faculty of Medicine, Alexandria University, Alexandria, EgyptCritical Care Medicine, Faculty of Medicine, Alexandria University, Alexandria, EgyptCritical Care Medicine, Faculty of Medicine, Alexandria University, Alexandria, EgyptABSTRACTBackground Fatal cardiovascular complications and acute respiratory distress syndrome (ARDS) account for the majority of SARS-CoV-2-associated deaths. The objective of this research was to find transthoracic echocardiography (TTE) of right ventricular (RV) dysfunction parameters that can be utilized to predict outcomes in individuals with severe COVID-19 pneumonia;Methods This observational research included 90 cases with severe COVID-19 pneumonia subjected to TTE on the day of admission and 3rd day to determine the relationship between severity, mortality in severe COVID-19 pneumonia and RV function parameters;Results TAPSE, SPAP, RVD, RV-WT, and RV-FAC had significant differences among the two groups. PaO2/FiO2 and average MAP were significantly correlated with all RV parameters. Adjusted multivariate regression analysis on day 1 showed that TAPSE and SPAP followed by RVFAC were significantly related to mortality. While on day 3, it was revealed that RVFAC then SPAP were significantly related to mortality. SPAP, with a cutoff point >46 mmHg, was the most sensitive parameter, while the most specific to predict mortality was TAPSE, with a cutoff point ≤15 mm.Conclusions In cases with severe COVID-19 pneumonia, prediction of mortality can be performed by measuring RV parameters by TTE with high sensitivity and specificity.https://www.tandfonline.com/doi/10.1080/11101849.2023.2204576Covid-19Pneumoniarightventricle |
| spellingShingle | Ali Salam Tayseer Zaytoun Tamer Abdallah Dina Zidan Echocardiographic assessment of right ventricular dysfunction and outcome in patients with severe Covid-19 Pneumonia Egyptian Journal of Anaesthesia Covid-19 Pneumonia right ventricle |
| title | Echocardiographic assessment of right ventricular dysfunction and outcome in patients with severe Covid-19 Pneumonia |
| title_full | Echocardiographic assessment of right ventricular dysfunction and outcome in patients with severe Covid-19 Pneumonia |
| title_fullStr | Echocardiographic assessment of right ventricular dysfunction and outcome in patients with severe Covid-19 Pneumonia |
| title_full_unstemmed | Echocardiographic assessment of right ventricular dysfunction and outcome in patients with severe Covid-19 Pneumonia |
| title_short | Echocardiographic assessment of right ventricular dysfunction and outcome in patients with severe Covid-19 Pneumonia |
| title_sort | echocardiographic assessment of right ventricular dysfunction and outcome in patients with severe covid 19 pneumonia |
| topic | Covid-19 Pneumonia right ventricle |
| url | https://www.tandfonline.com/doi/10.1080/11101849.2023.2204576 |
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