Histomorphological pattern of thyroid lesions: A prospective study
Background: Thyroid disorders are the commonest endocrine disorders worldwide. 15–20% of the thyroid nodules are indeterminate on cytological results. The definite diagnosis of these nodules is provided by examination of thyroidectomy. Objective: Aim was to describe various histomorphological patter...
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| Format: | Article |
| Language: | English |
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Al Ameen Medical College
2022-07-01
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| Series: | Al Ameen Journal of Medical Sciences |
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| Online Access: | http://ajms.alameenmedical.org/ArticlePDFs/9%20AJMS%20V15.N3.2022%20p%20222-226.pdf |
| _version_ | 1828267975584514048 |
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| author | Shruthi Shruthi Praveen Kumar Ram Bhat Parvathi S. Jigalur |
| author_facet | Shruthi Shruthi Praveen Kumar Ram Bhat Parvathi S. Jigalur |
| author_sort | Shruthi Shruthi |
| collection | DOAJ |
| description | Background: Thyroid disorders are the commonest endocrine disorders worldwide. 15–20% of the thyroid nodules are indeterminate on cytological results. The definite diagnosis of these nodules is provided by examination of thyroidectomy. Objective: Aim was to describe various histomorphological patterns of thyroid lesions and their frequency in relation to age and sex of the patients. Material and methods: A prospective cross-sectional study was carried out on all thyroidectomy specimens received in the department of Pathology from July 2015 to June 2017. A total of 110 specimens were included in the study. Statistical analysis: Statistical analysis was carried out using SPSS (version 14) software. Descriptive analysis was performed using frequencies and percentages. Results: Thyroid diseases were predominantly seen in females. Peak age of presentation was 3rd to 5th decade. Out of 110 cases studied, 77 cases (70%) were non neoplastic lesions and 33 cases were (30%) neoplastic lesions. Adenomatous goiter was the most common nonneoplastic lesion (84.41%) followed by Hashimoto thyroiditis (11.68%). Among neoplastic lesions, malignant neoplasms (23 cases, 69.69%) were more common than benign neoplasm (9 cases, 27.27%). Borderline neoplasm was seen in 3.03% (1 case). Papillary carcinoma was the most common malignant neoplasm (78.26%), which was predominantly seen in females (94.44%) and most common age of presentation was in 3rd to 4th decade (66.66%). Overall, the most common lesion was adenomatous goiter (59.09%) followed by papillary carcinoma (16.36%), Hashimoto’s thyroiditis (8.18%) and follicular adenoma (7.27%). Conclusion: Histopathological examination plays a major role in definitive diagnosis of thyroid lesions. Adenomatous goiter was the most common lesion followed by Papillary carcinoma which suggests increasing prevalence of thyroid malignancy in the population. |
| first_indexed | 2024-04-13T05:12:01Z |
| format | Article |
| id | doaj.art-552d024f24964cbabf5918fc18c6f1e1 |
| institution | Directory Open Access Journal |
| issn | 0974-1143 |
| language | English |
| last_indexed | 2024-04-13T05:12:01Z |
| publishDate | 2022-07-01 |
| publisher | Al Ameen Medical College |
| record_format | Article |
| series | Al Ameen Journal of Medical Sciences |
| spelling | doaj.art-552d024f24964cbabf5918fc18c6f1e12022-12-22T03:01:00ZengAl Ameen Medical CollegeAl Ameen Journal of Medical Sciences0974-11432022-07-011503222226Histomorphological pattern of thyroid lesions: A prospective studyShruthi Shruthi0Praveen Kumar Ram Bhat1Parvathi S. Jigalur2Department of Pathology, K.S. Hegde Medical Academy, Nitte (Deemed to be university), P.O Deralakatte, Mangaluru-575018, Karnataka, IndiaDepartmet of Surgery, K.S. Hegde Medical Academy, Nitte (Deemed to be university), P.O Deralakatte, Mangaluru-575018, Karnataka, IndiaDepartment of Pathology, Karnataka Institute of Medical Sciences , Vidya Nagar, Hubli-580021, Karnataka, IndiaBackground: Thyroid disorders are the commonest endocrine disorders worldwide. 15–20% of the thyroid nodules are indeterminate on cytological results. The definite diagnosis of these nodules is provided by examination of thyroidectomy. Objective: Aim was to describe various histomorphological patterns of thyroid lesions and their frequency in relation to age and sex of the patients. Material and methods: A prospective cross-sectional study was carried out on all thyroidectomy specimens received in the department of Pathology from July 2015 to June 2017. A total of 110 specimens were included in the study. Statistical analysis: Statistical analysis was carried out using SPSS (version 14) software. Descriptive analysis was performed using frequencies and percentages. Results: Thyroid diseases were predominantly seen in females. Peak age of presentation was 3rd to 5th decade. Out of 110 cases studied, 77 cases (70%) were non neoplastic lesions and 33 cases were (30%) neoplastic lesions. Adenomatous goiter was the most common nonneoplastic lesion (84.41%) followed by Hashimoto thyroiditis (11.68%). Among neoplastic lesions, malignant neoplasms (23 cases, 69.69%) were more common than benign neoplasm (9 cases, 27.27%). Borderline neoplasm was seen in 3.03% (1 case). Papillary carcinoma was the most common malignant neoplasm (78.26%), which was predominantly seen in females (94.44%) and most common age of presentation was in 3rd to 4th decade (66.66%). Overall, the most common lesion was adenomatous goiter (59.09%) followed by papillary carcinoma (16.36%), Hashimoto’s thyroiditis (8.18%) and follicular adenoma (7.27%). Conclusion: Histopathological examination plays a major role in definitive diagnosis of thyroid lesions. Adenomatous goiter was the most common lesion followed by Papillary carcinoma which suggests increasing prevalence of thyroid malignancy in the population.http://ajms.alameenmedical.org/ArticlePDFs/9%20AJMS%20V15.N3.2022%20p%20222-226.pdfthyroidectomyhistopathologyneoplastic lesionnon neoplastic lesion |
| spellingShingle | Shruthi Shruthi Praveen Kumar Ram Bhat Parvathi S. Jigalur Histomorphological pattern of thyroid lesions: A prospective study Al Ameen Journal of Medical Sciences thyroidectomy histopathology neoplastic lesion non neoplastic lesion |
| title | Histomorphological pattern of thyroid lesions: A prospective study |
| title_full | Histomorphological pattern of thyroid lesions: A prospective study |
| title_fullStr | Histomorphological pattern of thyroid lesions: A prospective study |
| title_full_unstemmed | Histomorphological pattern of thyroid lesions: A prospective study |
| title_short | Histomorphological pattern of thyroid lesions: A prospective study |
| title_sort | histomorphological pattern of thyroid lesions a prospective study |
| topic | thyroidectomy histopathology neoplastic lesion non neoplastic lesion |
| url | http://ajms.alameenmedical.org/ArticlePDFs/9%20AJMS%20V15.N3.2022%20p%20222-226.pdf |
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