On-Site Validation of a Microwave Breast Imaging System, before First Patient Study

This paper presents the Wavelia microwave breast imaging system that has been recently installed at the Galway University Hospital, Ireland, for a first-in-human pilot clinical test. Microwave breast imaging has been extensively investigated over the last two decades as an alternative imaging modali...

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Main Authors: Angie Fasoula, Luc Duchesne, Julio Daniel Gil Cano, Peter Lawrence, Guillaume Robin, Jean-Gael Bernard
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:Diagnostics
Subjects:
Online Access:http://www.mdpi.com/2075-4418/8/3/53
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author Angie Fasoula
Luc Duchesne
Julio Daniel Gil Cano
Peter Lawrence
Guillaume Robin
Jean-Gael Bernard
author_facet Angie Fasoula
Luc Duchesne
Julio Daniel Gil Cano
Peter Lawrence
Guillaume Robin
Jean-Gael Bernard
author_sort Angie Fasoula
collection DOAJ
description This paper presents the Wavelia microwave breast imaging system that has been recently installed at the Galway University Hospital, Ireland, for a first-in-human pilot clinical test. Microwave breast imaging has been extensively investigated over the last two decades as an alternative imaging modality that could potentially bring complementary information to state-of-the-art modalities such as X-ray mammography. Following an overview of the main working principles of this technology, the Wavelia imaging system architecture is presented, as are the radar signal processing algorithms that are used in forming the microwave images in which small tumors could be detectable for disease diagnosis. The methodology and specific quality metrics that have been developed to properly evaluate and validate the performance of the imaging system using complex breast phantoms that are scanned at controlled measurement conditions are also presented in the paper. Indicative results from the application of this methodology to the on-site validation of the imaging system after its installation at the hospital for pilot clinical testing are thoroughly presented and discussed. Given that the imaging system is still at the prototype level of development, a rigorous quality assessment and system validation at nominal operating conditions is very important in order to ensure high-quality clinical data collection.
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spelling doaj.art-552ff286bd5d406a9d055f45bbc94f452022-12-22T02:58:56ZengMDPI AGDiagnostics2075-44182018-08-01835310.3390/diagnostics8030053diagnostics8030053On-Site Validation of a Microwave Breast Imaging System, before First Patient StudyAngie Fasoula0Luc Duchesne1Julio Daniel Gil Cano2Peter Lawrence3Guillaume Robin4Jean-Gael Bernard5MVG Industries, 91140 Villebon sur Yvette, FranceMVG Industries, 91140 Villebon sur Yvette, FranceMVG Industries, 91140 Villebon sur Yvette, FranceMVG Industries, 91140 Villebon sur Yvette, FranceMVG Industries, 91140 Villebon sur Yvette, FranceMVG Industries, 91140 Villebon sur Yvette, FranceThis paper presents the Wavelia microwave breast imaging system that has been recently installed at the Galway University Hospital, Ireland, for a first-in-human pilot clinical test. Microwave breast imaging has been extensively investigated over the last two decades as an alternative imaging modality that could potentially bring complementary information to state-of-the-art modalities such as X-ray mammography. Following an overview of the main working principles of this technology, the Wavelia imaging system architecture is presented, as are the radar signal processing algorithms that are used in forming the microwave images in which small tumors could be detectable for disease diagnosis. The methodology and specific quality metrics that have been developed to properly evaluate and validate the performance of the imaging system using complex breast phantoms that are scanned at controlled measurement conditions are also presented in the paper. Indicative results from the application of this methodology to the on-site validation of the imaging system after its installation at the hospital for pilot clinical testing are thoroughly presented and discussed. Given that the imaging system is still at the prototype level of development, a rigorous quality assessment and system validation at nominal operating conditions is very important in order to ensure high-quality clinical data collection.http://www.mdpi.com/2075-4418/8/3/53breast cancer diagnosismicrowave imagingmedical radaron-site validationbreast phantoms
spellingShingle Angie Fasoula
Luc Duchesne
Julio Daniel Gil Cano
Peter Lawrence
Guillaume Robin
Jean-Gael Bernard
On-Site Validation of a Microwave Breast Imaging System, before First Patient Study
Diagnostics
breast cancer diagnosis
microwave imaging
medical radar
on-site validation
breast phantoms
title On-Site Validation of a Microwave Breast Imaging System, before First Patient Study
title_full On-Site Validation of a Microwave Breast Imaging System, before First Patient Study
title_fullStr On-Site Validation of a Microwave Breast Imaging System, before First Patient Study
title_full_unstemmed On-Site Validation of a Microwave Breast Imaging System, before First Patient Study
title_short On-Site Validation of a Microwave Breast Imaging System, before First Patient Study
title_sort on site validation of a microwave breast imaging system before first patient study
topic breast cancer diagnosis
microwave imaging
medical radar
on-site validation
breast phantoms
url http://www.mdpi.com/2075-4418/8/3/53
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