Fibronectin extra domain A as a drug delivery targeting epitope for rheumatoid arthritis

Fibronectin extra domain A as a drug delivery targeting epitope for rheumatoid arthritis

Abstract Objectives To assess the ability of monoclonal antibodies (mAbs) specific for fibronectin extra-domain A (FnEDA) to target diseased tissues of mouse collagen induced arthritis (mCIA) models. To explore the parameters of the targeting exhibited by anti-FnEDA mAbs including timing and locatio...

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Main Authors: Victor Z. Sun, Terry L. Melim, Soumya Mitra, Jamie E. Erickson, Shaughn H. Bryant, Avery Farnham, Susan Westmoreland, Heather Knight, Liang Zhang, Wendy Ritacco, Kristoff Homan, Lorenzo Benatuil, Annette J. Schwartz Sterman, Andrew D. Goodearl
Format: Article
Language:English
Published: BMC 2022-05-01
Series:Advances in Rheumatology
Online Access:https://doi.org/10.1186/s42358-022-00247-2

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