Optical Biomarkers for the Diagnosis of Osteoarthritis through Raman Spectroscopy: Radiological and Biochemical Validation Using Ex Vivo Human Cartilage Samples

Optical Biomarkers for the Diagnosis of Osteoarthritis through Raman Spectroscopy: Radiological and Biochemical Validation Using Ex Vivo Human Cartilage Samples

Osteoarthritis (OA) is the most common rheumatic disease, characterized by progressive articular cartilage degradation. Raman spectroscopy (RS) has been recently proposed as a label-free tool to detect molecular changes in musculoskeletal tissues. We used cartilage samples derived from human femoral...

Full description

Bibliographic Details
Main Authors: Paula Casal-Beiroa, Vanesa Balboa-Barreiro, Natividad Oreiro, Sonia Pértega-Díaz, Francisco J. Blanco, Joana Magalhães
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Diagnostics
Subjects:
optical biomarkers
osteoarthritis
K-L grade
glycosaminoglycans
total collagen
lipids
Online Access:https://www.mdpi.com/2075-4418/11/3/546

Similar Items

Similar Items