Expression of cartilage oligomeric matrix protein in periampullary adenocarcinoma is associated with pancreatobiliary-type morphology, higher levels of fibrosis and immune cell exclusion

Expression of cartilage oligomeric matrix protein in periampullary adenocarcinoma is associated with pancreatobiliary-type morphology, higher levels of fibrosis and immune cell exclusion

Cartilage oligomeric matrix protein (COMP) is an emerging regulator of tumor progression. The aim of this study was to evaluate the expression of COMP in periampullary adenocarcinoma with respect to prognostic value for survival and relapse, levels of fibrosis and infiltrating immune cells. COMP exp...

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Bibliographic Details
Main Authors: Konstantinos S. Papadakos, Sebastian Lundgren, Chrysostomi Gialeli, Patrick Micke, Artur Mezheyeuski, Jacob Elebro, Karin Jirström, Anna M. Blom
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:OncoImmunology
Subjects:
COMP
pancreatic cancer
immune cell exclusion
fibrosis
collagen
Online Access:https://www.tandfonline.com/doi/10.1080/2162402X.2022.2111906

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