Leprosy reaction and immune reconstitution syndrome in AIDS
The authors report seven cases of borderline leprosy in AIDS patients whose presentation form was of a type I reaction diagnosed soon HAART introduction, which led to the discussion of the immunological aspects involved in the reaction to leprosy and the immune reconstitution syndrome. The patients...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Instituto Lauro de Souza Lima
2008-06-01
|
| Series: | Hansenologia Internationalis |
| Online Access: | https://periodicos.saude.sp.gov.br/hansenologia/article/view/35176 |
| _version_ | 1827583339423334400 |
|---|---|
| author | Trope Beatriz Moritz Lenzi Maria Elisa Ribeiro Maceira Juan Piñeiro Barroso Paulo Feijó Oliveira Maria Leide W. de |
| author_facet | Trope Beatriz Moritz Lenzi Maria Elisa Ribeiro Maceira Juan Piñeiro Barroso Paulo Feijó Oliveira Maria Leide W. de |
| author_sort | Trope Beatriz Moritz |
| collection | DOAJ |
| description |
The authors report seven cases of borderline leprosy in AIDS patients whose presentation form was of a type I reaction diagnosed soon HAART introduction, which led to the discussion of the immunological aspects involved in the reaction to leprosy and the immune reconstitution syndrome. The patients were in frank AIDS-induced immune deterioration, which was the reason they met the criteria to initiate HAART treatment. It is likely that due to this fact, the amount of CD4 cells increased at the same time that a reduction of the viral load occurred, allowing the installation of a basically Th1 immunological profile. Therefore, the leprosy infection, which was dormant and unable to express itself was exteriorized in the form of a reverse reaction.
|
| first_indexed | 2024-03-08T23:04:22Z |
| format | Article |
| id | doaj.art-5535cf2d72474a4381b14c5eb4018bb4 |
| institution | Directory Open Access Journal |
| issn | 1982-5161 |
| language | English |
| last_indexed | 2024-03-08T23:04:22Z |
| publishDate | 2008-06-01 |
| publisher | Instituto Lauro de Souza Lima |
| record_format | Article |
| series | Hansenologia Internationalis |
| spelling | doaj.art-5535cf2d72474a4381b14c5eb4018bb42023-12-15T14:07:35ZengInstituto Lauro de Souza LimaHansenologia Internationalis1982-51612008-06-0133110.47878/hi.2008.v33.35176Leprosy reaction and immune reconstitution syndrome in AIDSTrope Beatriz Moritz0Lenzi Maria Elisa Ribeiro1Maceira Juan Piñeiro2Barroso Paulo Feijó3Oliveira Maria Leide W. de4Dermatology sector, Clementino Fraga Filho University Hospital, School of Medicine, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.Dermatology sector, Clementino Fraga Filho University Hospital, School of Medicine, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.Dermatology sector, Clementino Fraga Filho University Hospital, School of Medicine, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.Dermatology sector, Clementino Fraga Filho University Hospital, School of Medicine, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.Dermatology sector, Clementino Fraga Filho University Hospital, School of Medicine, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil. The authors report seven cases of borderline leprosy in AIDS patients whose presentation form was of a type I reaction diagnosed soon HAART introduction, which led to the discussion of the immunological aspects involved in the reaction to leprosy and the immune reconstitution syndrome. The patients were in frank AIDS-induced immune deterioration, which was the reason they met the criteria to initiate HAART treatment. It is likely that due to this fact, the amount of CD4 cells increased at the same time that a reduction of the viral load occurred, allowing the installation of a basically Th1 immunological profile. Therefore, the leprosy infection, which was dormant and unable to express itself was exteriorized in the form of a reverse reaction. https://periodicos.saude.sp.gov.br/hansenologia/article/view/35176 |
| spellingShingle | Trope Beatriz Moritz Lenzi Maria Elisa Ribeiro Maceira Juan Piñeiro Barroso Paulo Feijó Oliveira Maria Leide W. de Leprosy reaction and immune reconstitution syndrome in AIDS Hansenologia Internationalis |
| title | Leprosy reaction and immune reconstitution syndrome in AIDS |
| title_full | Leprosy reaction and immune reconstitution syndrome in AIDS |
| title_fullStr | Leprosy reaction and immune reconstitution syndrome in AIDS |
| title_full_unstemmed | Leprosy reaction and immune reconstitution syndrome in AIDS |
| title_short | Leprosy reaction and immune reconstitution syndrome in AIDS |
| title_sort | leprosy reaction and immune reconstitution syndrome in aids |
| url | https://periodicos.saude.sp.gov.br/hansenologia/article/view/35176 |
| work_keys_str_mv | AT tropebeatrizmoritz leprosyreactionandimmunereconstitutionsyndromeinaids AT lenzimariaelisaribeiro leprosyreactionandimmunereconstitutionsyndromeinaids AT maceirajuanpineiro leprosyreactionandimmunereconstitutionsyndromeinaids AT barrosopaulofeijo leprosyreactionandimmunereconstitutionsyndromeinaids AT oliveiramarialeidewde leprosyreactionandimmunereconstitutionsyndromeinaids |