Clinical analysis of 312 patients with stage IB1-IIA2 cervical squamous cell carcinoma and research on the influencing factors of postoperative recurrence
Highlights 1. The relationship between postoperative HPV infection and cervical cancer recurrences was explored for the first time. 2. The genotypes and viral loads of 15 types of HR-HPV were determined. 3. Continuous HR-HPV positivity after surgery and deep 1/3 interstitial infiltration were risk f...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-02-01
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| Series: | BMC Women's Health |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12905-023-02159-9 |
| _version_ | 1797863671379001344 |
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| author | Jia Zeng Jing Zuo Ning Li HongWen Yao YuanYuan Zhang YuXi Zhao TianTian Wang Lin Xiu Jian Li Jing Yu LeiLei Liang LingYing Wu |
| author_facet | Jia Zeng Jing Zuo Ning Li HongWen Yao YuanYuan Zhang YuXi Zhao TianTian Wang Lin Xiu Jian Li Jing Yu LeiLei Liang LingYing Wu |
| author_sort | Jia Zeng |
| collection | DOAJ |
| description | Highlights 1. The relationship between postoperative HPV infection and cervical cancer recurrences was explored for the first time. 2. The genotypes and viral loads of 15 types of HR-HPV were determined. 3. Continuous HR-HPV positivity after surgery and deep 1/3 interstitial infiltration were risk factors for the recurrence of cervical cancer. |
| first_indexed | 2024-04-09T22:39:15Z |
| format | Article |
| id | doaj.art-5538a8c3c51a4bab89d3fc385d3f53f7 |
| institution | Directory Open Access Journal |
| issn | 1472-6874 |
| language | English |
| last_indexed | 2024-04-09T22:39:15Z |
| publishDate | 2023-02-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Women's Health |
| spelling | doaj.art-5538a8c3c51a4bab89d3fc385d3f53f72023-03-22T12:15:32ZengBMCBMC Women's Health1472-68742023-02-012311810.1186/s12905-023-02159-9Clinical analysis of 312 patients with stage IB1-IIA2 cervical squamous cell carcinoma and research on the influencing factors of postoperative recurrenceJia Zeng0Jing Zuo1Ning Li2HongWen Yao3YuanYuan Zhang4YuXi Zhao5TianTian Wang6Lin Xiu7Jian Li8Jing Yu9LeiLei Liang10LingYing Wu11Department of Gynecologic Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical CollegeDepartment of Gynecologic Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical CollegeDepartment of Gynecologic Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical CollegeDepartment of Gynecologic Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical CollegeDepartment of Gynecologic Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical CollegeDepartment of Gynecologic Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical CollegeDepartment of Gynecologic Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical CollegeDepartment of Gynecologic Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical CollegeDepartment of Gynecologic Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical CollegeDepartment of Gynecologic Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical CollegeDepartment of Gynecologic Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical CollegeDepartment of Gynecologic Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical CollegeHighlights 1. The relationship between postoperative HPV infection and cervical cancer recurrences was explored for the first time. 2. The genotypes and viral loads of 15 types of HR-HPV were determined. 3. Continuous HR-HPV positivity after surgery and deep 1/3 interstitial infiltration were risk factors for the recurrence of cervical cancer.https://doi.org/10.1186/s12905-023-02159-9Cervical cancerRadical hysterectomyHuman papillomavirusViral loadRecurrence |
| spellingShingle | Jia Zeng Jing Zuo Ning Li HongWen Yao YuanYuan Zhang YuXi Zhao TianTian Wang Lin Xiu Jian Li Jing Yu LeiLei Liang LingYing Wu Clinical analysis of 312 patients with stage IB1-IIA2 cervical squamous cell carcinoma and research on the influencing factors of postoperative recurrence BMC Women's Health Cervical cancer Radical hysterectomy Human papillomavirus Viral load Recurrence |
| title | Clinical analysis of 312 patients with stage IB1-IIA2 cervical squamous cell carcinoma and research on the influencing factors of postoperative recurrence |
| title_full | Clinical analysis of 312 patients with stage IB1-IIA2 cervical squamous cell carcinoma and research on the influencing factors of postoperative recurrence |
| title_fullStr | Clinical analysis of 312 patients with stage IB1-IIA2 cervical squamous cell carcinoma and research on the influencing factors of postoperative recurrence |
| title_full_unstemmed | Clinical analysis of 312 patients with stage IB1-IIA2 cervical squamous cell carcinoma and research on the influencing factors of postoperative recurrence |
| title_short | Clinical analysis of 312 patients with stage IB1-IIA2 cervical squamous cell carcinoma and research on the influencing factors of postoperative recurrence |
| title_sort | clinical analysis of 312 patients with stage ib1 iia2 cervical squamous cell carcinoma and research on the influencing factors of postoperative recurrence |
| topic | Cervical cancer Radical hysterectomy Human papillomavirus Viral load Recurrence |
| url | https://doi.org/10.1186/s12905-023-02159-9 |
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