Limb Remote Ischemic Conditioning Promotes Neurogenesis after Cerebral Ischemia by Modulating miR-449b/Notch1 Pathway in Mice

Limb Remote Ischemic Conditioning Promotes Neurogenesis after Cerebral Ischemia by Modulating miR-449b/Notch1 Pathway in Mice

Neurogenesis plays an important role in the prognosis of stroke patients and is known to be promoted by the activation of the Notch1 signaling pathway. Studies on the airway epithelium have shown that miR-449b represses the Notch pathway. The study aimed to investigate whether limb remote ischemic c...

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Bibliographic Details
Main Authors: Sijie Li, Yong Yang, Ning Li, Haiyan Li, Jiali Xu, Wenbo Zhao, Xiaojie Wang, Linqing Ma, Chen Gao, Yuchuan Ding, Xunming Ji, Changhong Ren
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Biomolecules
Subjects:
ischemic stroke
neurogenesis
limb remote ischemic conditioning
miR-449b
Notch1
Online Access:https://www.mdpi.com/2218-273X/12/8/1137

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