A Decrease in Maternal Iron Levels Is the Predominant Factor Suppressing Hepcidin during Pregnancy in Mice

A Decrease in Maternal Iron Levels Is the Predominant Factor Suppressing Hepcidin during Pregnancy in Mice

In order to supply adequate iron during pregnancy, the levels of the iron regulatory hormone hepcidin in the maternal circulation are suppressed, thereby increasing dietary iron absorption and storage iron release. Whether this decrease in maternal hepcidin is caused by changes in factors known to r...

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Bibliographic Details
Main Authors: Sheridan L. Helman, Sarah J. Wilkins, Jennifer C. J. Chan, Gunter Hartel, Daniel F. Wallace, Gregory J. Anderson, David M. Frazer
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:International Journal of Molecular Sciences
Subjects:
pregnancy
iron homeostasis
hepcidin
Online Access:https://www.mdpi.com/1422-0067/24/18/14379

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