Actiflagelin, a new sperm activator isolated from Walterinnesia aegyptia venom using phenotypic screening

Actiflagelin, a new sperm activator isolated from Walterinnesia aegyptia venom using phenotypic screening

Abstract Background Sperm contains a wealth of cell surface receptors and ion channels that are required for most of its basic functions such as motility and acrosome reaction. Conversely, animal venoms are enriched in bioactive compounds that primarily target those ion channels and cell surface re...

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Bibliographic Details
Main Authors:	Tarek Mohamed Abd El-Aziz, Sawsan Al Khoury, Lucie Jaquillard, Mathilde Triquigneaux, Guillaume Martinez, Sandrine Bourgoin-Voillard, Michel Sève, Christophe Arnoult, Rémy Beroud, Michel De Waard
Format:	Article
Language:	English
Published:	SciELO 2018-02-01
Series:	Journal of Venomous Animals and Toxins including Tropical Diseases
Subjects:	Snake venom Walterinnesia aegyptia Bioactive compounds Fertility Sperm motility Venomics Tandem mass spectrometry De novo sequencing Edman degradation
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992018000100301&lng=en&tlng=en

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