Anti-oxidant and hepatoprotective activities of total flavonoids of Indocalamus latifolius
The total flavonoids of Indocalamus latifolius were evaluated in term of their anti-oxidant and hepatoprotective activities. The results showed that in vitrohepatoprotective and anti-oxidant activities of total flavonoids at doses of 200 and 400 mg/kg and 100 mg/kg, respectively, were comparable to...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Bangladesh Pharmacological Society
2015-09-01
|
Series: | Bangladesh Journal of Pharmacology |
Subjects: | |
Online Access: | https://www.banglajol.info/index.php/BJP/article/view/23496 |
_version_ | 1811278654396694528 |
---|---|
author | Juan Tan Li Shenghua Junying Zeng Xianjin Wu |
author_facet | Juan Tan Li Shenghua Junying Zeng Xianjin Wu |
author_sort | Juan Tan |
collection | DOAJ |
description | The total flavonoids of Indocalamus latifolius were evaluated in term of their anti-oxidant and hepatoprotective activities. The results showed that in vitrohepatoprotective and anti-oxidant activities of total flavonoids at doses of 200 and 400 mg/kg and 100 mg/kg, respectively, were comparable to those of the known hepatoprotective drug silymarin at 100 mg/kg. These data were supplemented with histopathological studies of rat liver sections. Seven of the main flavonoid compounds purified by column chromatography using silica gel, sephadex LH-20 and develosil ODS, and determined to be vitexin, orientin, isovitexin, homoorientin, tricin, tricin-7-O-β-D-glucopyranoside and quercetin-3-O-glucopyranoside. |
first_indexed | 2024-04-13T00:41:08Z |
format | Article |
id | doaj.art-5541ace6e58a42a5ae72acf00ebbdada |
institution | Directory Open Access Journal |
issn | 1991-0088 |
language | English |
last_indexed | 2024-04-13T00:41:08Z |
publishDate | 2015-09-01 |
publisher | Bangladesh Pharmacological Society |
record_format | Article |
series | Bangladesh Journal of Pharmacology |
spelling | doaj.art-5541ace6e58a42a5ae72acf00ebbdada2022-12-22T03:10:11ZengBangladesh Pharmacological SocietyBangladesh Journal of Pharmacology1991-00882015-09-0110410.3329/bjp.v10i4.23496Anti-oxidant and hepatoprotective activities of total flavonoids of Indocalamus latifoliusJuan Tan0Li Shenghua1Junying Zeng2Xianjin Wu3The Department of Life Science, Huaihua University, Huaihua 418008The Department of Life Science, Huaihua University, Huaihua 418008The Department of Life Science, Huaihua University, Huaihua 418008The Department of Life Science, Huaihua University, Huaihua 418008The total flavonoids of Indocalamus latifolius were evaluated in term of their anti-oxidant and hepatoprotective activities. The results showed that in vitrohepatoprotective and anti-oxidant activities of total flavonoids at doses of 200 and 400 mg/kg and 100 mg/kg, respectively, were comparable to those of the known hepatoprotective drug silymarin at 100 mg/kg. These data were supplemented with histopathological studies of rat liver sections. Seven of the main flavonoid compounds purified by column chromatography using silica gel, sephadex LH-20 and develosil ODS, and determined to be vitexin, orientin, isovitexin, homoorientin, tricin, tricin-7-O-β-D-glucopyranoside and quercetin-3-O-glucopyranoside.https://www.banglajol.info/index.php/BJP/article/view/23496Anti-oxidantFlavonoidHepatoprotectiveIndocalamus latifolius |
spellingShingle | Juan Tan Li Shenghua Junying Zeng Xianjin Wu Anti-oxidant and hepatoprotective activities of total flavonoids of Indocalamus latifolius Bangladesh Journal of Pharmacology Anti-oxidant Flavonoid Hepatoprotective Indocalamus latifolius |
title | Anti-oxidant and hepatoprotective activities of total flavonoids of Indocalamus latifolius |
title_full | Anti-oxidant and hepatoprotective activities of total flavonoids of Indocalamus latifolius |
title_fullStr | Anti-oxidant and hepatoprotective activities of total flavonoids of Indocalamus latifolius |
title_full_unstemmed | Anti-oxidant and hepatoprotective activities of total flavonoids of Indocalamus latifolius |
title_short | Anti-oxidant and hepatoprotective activities of total flavonoids of Indocalamus latifolius |
title_sort | anti oxidant and hepatoprotective activities of total flavonoids of indocalamus latifolius |
topic | Anti-oxidant Flavonoid Hepatoprotective Indocalamus latifolius |
url | https://www.banglajol.info/index.php/BJP/article/view/23496 |
work_keys_str_mv | AT juantan antioxidantandhepatoprotectiveactivitiesoftotalflavonoidsofindocalamuslatifolius AT lishenghua antioxidantandhepatoprotectiveactivitiesoftotalflavonoidsofindocalamuslatifolius AT junyingzeng antioxidantandhepatoprotectiveactivitiesoftotalflavonoidsofindocalamuslatifolius AT xianjinwu antioxidantandhepatoprotectiveactivitiesoftotalflavonoidsofindocalamuslatifolius |