Anti-oxidant and hepatoprotective activities of total flavonoids of Indocalamus latifolius

The total flavonoids of Indocalamus latifolius were evaluated in term of their anti-oxidant and hepatoprotective activities. The results showed that in vitrohepatoprotective and anti-oxidant activities of total flavonoids at doses of 200 and 400 mg/kg and 100 mg/kg, respectively, were comparable to...

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Main Authors: Juan Tan, Li Shenghua, Junying Zeng, Xianjin Wu
Format: Article
Language:English
Published: Bangladesh Pharmacological Society 2015-09-01
Series:Bangladesh Journal of Pharmacology
Subjects:
Online Access:https://www.banglajol.info/index.php/BJP/article/view/23496
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author Juan Tan
Li Shenghua
Junying Zeng
Xianjin Wu
author_facet Juan Tan
Li Shenghua
Junying Zeng
Xianjin Wu
author_sort Juan Tan
collection DOAJ
description The total flavonoids of Indocalamus latifolius were evaluated in term of their anti-oxidant and hepatoprotective activities. The results showed that in vitrohepatoprotective and anti-oxidant activities of total flavonoids at doses of 200 and 400 mg/kg and 100 mg/kg, respectively, were comparable to those of the known hepatoprotective drug silymarin at 100 mg/kg. These data were supplemented with histopathological studies of rat liver sections. Seven of the main flavonoid compounds purified by column chromatography using silica gel, sephadex LH-20 and develosil ODS, and determined to be vitexin, orientin, isovitexin, homoorientin, tricin, tricin-7-O-β-D-glucopyranoside and quercetin-3-O-glucopyranoside.
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spelling doaj.art-5541ace6e58a42a5ae72acf00ebbdada2022-12-22T03:10:11ZengBangladesh Pharmacological SocietyBangladesh Journal of Pharmacology1991-00882015-09-0110410.3329/bjp.v10i4.23496Anti-oxidant and hepatoprotective activities of total flavonoids of Indocalamus latifoliusJuan Tan0Li Shenghua1Junying Zeng2Xianjin Wu3The Department of Life Science, Huaihua University, Huaihua 418008The Department of Life Science, Huaihua University, Huaihua 418008The Department of Life Science, Huaihua University, Huaihua 418008The Department of Life Science, Huaihua University, Huaihua 418008The total flavonoids of Indocalamus latifolius were evaluated in term of their anti-oxidant and hepatoprotective activities. The results showed that in vitrohepatoprotective and anti-oxidant activities of total flavonoids at doses of 200 and 400 mg/kg and 100 mg/kg, respectively, were comparable to those of the known hepatoprotective drug silymarin at 100 mg/kg. These data were supplemented with histopathological studies of rat liver sections. Seven of the main flavonoid compounds purified by column chromatography using silica gel, sephadex LH-20 and develosil ODS, and determined to be vitexin, orientin, isovitexin, homoorientin, tricin, tricin-7-O-β-D-glucopyranoside and quercetin-3-O-glucopyranoside.https://www.banglajol.info/index.php/BJP/article/view/23496Anti-oxidantFlavonoidHepatoprotectiveIndocalamus latifolius
spellingShingle Juan Tan
Li Shenghua
Junying Zeng
Xianjin Wu
Anti-oxidant and hepatoprotective activities of total flavonoids of Indocalamus latifolius
Bangladesh Journal of Pharmacology
Anti-oxidant
Flavonoid
Hepatoprotective
Indocalamus latifolius
title Anti-oxidant and hepatoprotective activities of total flavonoids of Indocalamus latifolius
title_full Anti-oxidant and hepatoprotective activities of total flavonoids of Indocalamus latifolius
title_fullStr Anti-oxidant and hepatoprotective activities of total flavonoids of Indocalamus latifolius
title_full_unstemmed Anti-oxidant and hepatoprotective activities of total flavonoids of Indocalamus latifolius
title_short Anti-oxidant and hepatoprotective activities of total flavonoids of Indocalamus latifolius
title_sort anti oxidant and hepatoprotective activities of total flavonoids of indocalamus latifolius
topic Anti-oxidant
Flavonoid
Hepatoprotective
Indocalamus latifolius
url https://www.banglajol.info/index.php/BJP/article/view/23496
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AT lishenghua antioxidantandhepatoprotectiveactivitiesoftotalflavonoidsofindocalamuslatifolius
AT junyingzeng antioxidantandhepatoprotectiveactivitiesoftotalflavonoidsofindocalamuslatifolius
AT xianjinwu antioxidantandhepatoprotectiveactivitiesoftotalflavonoidsofindocalamuslatifolius