Tight Junction Proteins and Signaling Pathways in Cancer and Inflammation: A Functional Crosstalk

Tight Junction Proteins and Signaling Pathways in Cancer and Inflammation: A Functional Crosstalk

The ability of epithelial cells to organize through cell–cell adhesion into a functioning epithelium serves the purpose of a tight epithelial protective barrier. Contacts between adjacent cells are made up of tight junctions (TJ), adherens junctions (AJ), and desmosomes with unique cellular function...

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Bibliographic Details
Main Authors: Ajaz A. Bhat, Srijayaprakash Uppada, Iman W. Achkar, Sheema Hashem, Santosh K. Yadav, Muralitharan Shanmugakonar, Hamda A. Al-Naemi, Mohammad Haris, Shahab Uddin
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Physiology
Subjects:
tight junction
claudin
signaling molecules
tumor
metastasis
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2018.01942/full

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