The Effects of Anthrax Lethal Toxin on Host Barrier Function

The Effects of Anthrax Lethal Toxin on Host Barrier Function

The pathological actions of anthrax toxin require the activities of its edema factor (EF) and lethal factor (LF) enzyme components, which gain intracellular access via its receptor-binding component, protective antigen (PA). LF is a metalloproteinase with specificity for selected mitogen-activated p...

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Bibliographic Details
Main Authors: David M. Frucht, Roger D. Auth, Tao Xie
Format: Article
Language:English
Published: MDPI AG 2011-06-01
Series:Toxins
Subjects:
anthrax lethal toxin
barrier function
bacteria
infection
intestine
endothelium
epithelium
blood-brain barrier
Online Access:http://www.mdpi.com/2072-6651/3/6/591/

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