PROGRESSION OF SERUM MARKERS IN CHRONIC LIVER DISEASE PRODUCED BY CHRONIC VIRAL HEPATITIS B, C AND CO-INFECTION
Background: Chronic liver disease represents a major cause of morbidity and mortality worldwide. The objectives of the study were to determine and compare values of serum markers in subgroups; category-wise (MCTP scoring system) as well as infection-wise among patients of HBV, HBC and co-infections....
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| Format: | Article |
| Language: | English |
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Gomal Medical College, D.I.Khan, Pakistan
2017-12-01
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| Series: | Gomal Journal of Medical Sciences |
| Subjects: | |
| Online Access: | http://gjms.com.pk/ojs24/index.php/gjms/article/view/1634 |
| _version_ | 1818400576738689024 |
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| author | Aamir Nazir Alruba Taimoor Raisa Naz Sadaf Anwar Qureshi |
| author_facet | Aamir Nazir Alruba Taimoor Raisa Naz Sadaf Anwar Qureshi |
| author_sort | Aamir Nazir |
| collection | DOAJ |
| description | Background: Chronic liver disease represents a major cause of morbidity and mortality worldwide. The objectives of the study were to determine and compare values of serum markers in subgroups; category-wise (MCTP scoring system) as well as infection-wise among patients of HBV, HBC and co-infections.
Material & Methods: A cross-sectional study was conducted in the Department of Medicine, Lahore General Hospital, Lahore in 2010. Sample size was patients of chronic HBV, HCV, and co-infections. The patients were grouped with 25 subjects each in HB, HC and co-infection. Non-probability-convenience sampling was used for data collection. Demographic variables were sex and age in years. Research variables were AST/ALT ratio, prothrombin time, platelet conunt, serum albumin and serum bilirubin. Continuous variables like biochemical markers were analyzed as mean ±standard deviation (±SD) whereas categorical variables were analyzed as count and percentages using SPSS version 20.0. One-way ANOVA was applied to observe group mean differences.
Results: Out of the 75 subjects, 51(68.0%) were males and 24(32.0%) were females. The mean ±SD age was 44.69 ±7.423 years. There was a significant difference in AST/ALT ratio in chronic HBV group only (p |
| first_indexed | 2024-12-14T07:38:46Z |
| format | Article |
| id | doaj.art-554ed543cdb9459e86b18133c14bd168 |
| institution | Directory Open Access Journal |
| issn | 1819-7973 1997-2067 |
| language | English |
| last_indexed | 2024-12-14T07:38:46Z |
| publishDate | 2017-12-01 |
| publisher | Gomal Medical College, D.I.Khan, Pakistan |
| record_format | Article |
| series | Gomal Journal of Medical Sciences |
| spelling | doaj.art-554ed543cdb9459e86b18133c14bd1682022-12-21T23:11:05ZengGomal Medical College, D.I.Khan, PakistanGomal Journal of Medical Sciences1819-79731997-20672017-12-01152937PROGRESSION OF SERUM MARKERS IN CHRONIC LIVER DISEASE PRODUCED BY CHRONIC VIRAL HEPATITIS B, C AND CO-INFECTIONAamir Nazir0Alruba Taimoor1Raisa Naz2Sadaf Anwar Qureshi3Ayub Medical College, Abbottabad, PakistanAyub Medical College, Abbottabad, PakistanAyub Medical College, AbbottabadAyub Medical College, AbbottabadBackground: Chronic liver disease represents a major cause of morbidity and mortality worldwide. The objectives of the study were to determine and compare values of serum markers in subgroups; category-wise (MCTP scoring system) as well as infection-wise among patients of HBV, HBC and co-infections. Material & Methods: A cross-sectional study was conducted in the Department of Medicine, Lahore General Hospital, Lahore in 2010. Sample size was patients of chronic HBV, HCV, and co-infections. The patients were grouped with 25 subjects each in HB, HC and co-infection. Non-probability-convenience sampling was used for data collection. Demographic variables were sex and age in years. Research variables were AST/ALT ratio, prothrombin time, platelet conunt, serum albumin and serum bilirubin. Continuous variables like biochemical markers were analyzed as mean ±standard deviation (±SD) whereas categorical variables were analyzed as count and percentages using SPSS version 20.0. One-way ANOVA was applied to observe group mean differences. Results: Out of the 75 subjects, 51(68.0%) were males and 24(32.0%) were females. The mean ±SD age was 44.69 ±7.423 years. There was a significant difference in AST/ALT ratio in chronic HBV group only (phttp://gjms.com.pk/ojs24/index.php/gjms/article/view/1634chronic liver diseaseviral hepatitisserum markersmodified child-turcotte-pugh score. |
| spellingShingle | Aamir Nazir Alruba Taimoor Raisa Naz Sadaf Anwar Qureshi PROGRESSION OF SERUM MARKERS IN CHRONIC LIVER DISEASE PRODUCED BY CHRONIC VIRAL HEPATITIS B, C AND CO-INFECTION Gomal Journal of Medical Sciences chronic liver disease viral hepatitis serum markers modified child-turcotte-pugh score. |
| title | PROGRESSION OF SERUM MARKERS IN CHRONIC LIVER DISEASE PRODUCED BY CHRONIC VIRAL HEPATITIS B, C AND CO-INFECTION |
| title_full | PROGRESSION OF SERUM MARKERS IN CHRONIC LIVER DISEASE PRODUCED BY CHRONIC VIRAL HEPATITIS B, C AND CO-INFECTION |
| title_fullStr | PROGRESSION OF SERUM MARKERS IN CHRONIC LIVER DISEASE PRODUCED BY CHRONIC VIRAL HEPATITIS B, C AND CO-INFECTION |
| title_full_unstemmed | PROGRESSION OF SERUM MARKERS IN CHRONIC LIVER DISEASE PRODUCED BY CHRONIC VIRAL HEPATITIS B, C AND CO-INFECTION |
| title_short | PROGRESSION OF SERUM MARKERS IN CHRONIC LIVER DISEASE PRODUCED BY CHRONIC VIRAL HEPATITIS B, C AND CO-INFECTION |
| title_sort | progression of serum markers in chronic liver disease produced by chronic viral hepatitis b c and co infection |
| topic | chronic liver disease viral hepatitis serum markers modified child-turcotte-pugh score. |
| url | http://gjms.com.pk/ojs24/index.php/gjms/article/view/1634 |
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