Seeking patterns of antibiotic resistance in ATLAS, an open, raw MIC database with patient metadata

Pathogens are typically classified as ‘antibiotic-resistant’ for clinical purposes based on cut-off values of minimum inhibitory concentrations (MICs). In this study, the authors explore quantitative values of MICs using the global ‘ATLAS’ database of pathogen-antibiotic pairs, describe trends in re...

Full description

Bibliographic Details
Main Authors: Pablo Catalán, Emily Wood, Jessica M. A. Blair, Ivana Gudelj, Jonathan R. Iredell, Robert E. Beardmore
Format: Article
Language:English
Published: Nature Portfolio 2022-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-30635-7
_version_ 1828228448926040064
author Pablo Catalán
Emily Wood
Jessica M. A. Blair
Ivana Gudelj
Jonathan R. Iredell
Robert E. Beardmore
author_facet Pablo Catalán
Emily Wood
Jessica M. A. Blair
Ivana Gudelj
Jonathan R. Iredell
Robert E. Beardmore
author_sort Pablo Catalán
collection DOAJ
description Pathogens are typically classified as ‘antibiotic-resistant’ for clinical purposes based on cut-off values of minimum inhibitory concentrations (MICs). In this study, the authors explore quantitative values of MICs using the global ‘ATLAS’ database of pathogen-antibiotic pairs, describe trends in resistance, and compare results to other antibiotic resistance surveillance data.
first_indexed 2024-04-12T18:20:33Z
format Article
id doaj.art-554efb0606b5483784bf9d3ba61d6eca
institution Directory Open Access Journal
issn 2041-1723
language English
last_indexed 2024-04-12T18:20:33Z
publishDate 2022-05-01
publisher Nature Portfolio
record_format Article
series Nature Communications
spelling doaj.art-554efb0606b5483784bf9d3ba61d6eca2022-12-22T03:21:26ZengNature PortfolioNature Communications2041-17232022-05-0113111510.1038/s41467-022-30635-7Seeking patterns of antibiotic resistance in ATLAS, an open, raw MIC database with patient metadataPablo Catalán0Emily Wood1Jessica M. A. Blair2Ivana Gudelj3Jonathan R. Iredell4Robert E. Beardmore5Biosciences, College of Life and Environmental Sciences, University of ExeterBiosciences, College of Life and Environmental Sciences, University of ExeterInstitute of Microbiology and Infection, College of Medical and Dental Sciences, University of BirminghamBiosciences, College of Life and Environmental Sciences, University of ExeterCentre for Infectious Diseases and Microbiology, Westmead Institute for Medical ResearchBiosciences, College of Life and Environmental Sciences, University of ExeterPathogens are typically classified as ‘antibiotic-resistant’ for clinical purposes based on cut-off values of minimum inhibitory concentrations (MICs). In this study, the authors explore quantitative values of MICs using the global ‘ATLAS’ database of pathogen-antibiotic pairs, describe trends in resistance, and compare results to other antibiotic resistance surveillance data.https://doi.org/10.1038/s41467-022-30635-7
spellingShingle Pablo Catalán
Emily Wood
Jessica M. A. Blair
Ivana Gudelj
Jonathan R. Iredell
Robert E. Beardmore
Seeking patterns of antibiotic resistance in ATLAS, an open, raw MIC database with patient metadata
Nature Communications
title Seeking patterns of antibiotic resistance in ATLAS, an open, raw MIC database with patient metadata
title_full Seeking patterns of antibiotic resistance in ATLAS, an open, raw MIC database with patient metadata
title_fullStr Seeking patterns of antibiotic resistance in ATLAS, an open, raw MIC database with patient metadata
title_full_unstemmed Seeking patterns of antibiotic resistance in ATLAS, an open, raw MIC database with patient metadata
title_short Seeking patterns of antibiotic resistance in ATLAS, an open, raw MIC database with patient metadata
title_sort seeking patterns of antibiotic resistance in atlas an open raw mic database with patient metadata
url https://doi.org/10.1038/s41467-022-30635-7
work_keys_str_mv AT pablocatalan seekingpatternsofantibioticresistanceinatlasanopenrawmicdatabasewithpatientmetadata
AT emilywood seekingpatternsofantibioticresistanceinatlasanopenrawmicdatabasewithpatientmetadata
AT jessicamablair seekingpatternsofantibioticresistanceinatlasanopenrawmicdatabasewithpatientmetadata
AT ivanagudelj seekingpatternsofantibioticresistanceinatlasanopenrawmicdatabasewithpatientmetadata
AT jonathanriredell seekingpatternsofantibioticresistanceinatlasanopenrawmicdatabasewithpatientmetadata
AT robertebeardmore seekingpatternsofantibioticresistanceinatlasanopenrawmicdatabasewithpatientmetadata