Feasibility of community at-home dried blood spot collection combined with pooled reverse transcription PCR as a viable and convenient method for malaria epidemiology studies

Feasibility of community at-home dried blood spot collection combined with pooled reverse transcription PCR as a viable and convenient method for malaria epidemiology studies

Abstract Background Many Plasmodium infections in endemic regions exist at densities below the limit of detection of standard diagnostic tools. These infections threaten control efforts and may impact vaccine and therapeutic drug studies. Simple, cost-effective methods are needed to study the natura...

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Bibliographic Details
Main Authors: Dianna E. B. Hergott, Tonny J. Owalla, Jennifer E. Balkus, Bernadette Apio, Jimmy Lema, Barbara Cemeri, Andrew Akileng, Annette M. Seilie, Chris Chavtur, Weston Staubus, Ming Chang, Thomas G. Egwang, Sean C. Murphy
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Malaria Journal
Subjects:
Plasmodium falciparum
Asymptomatic malaria
Asymptomatic
DBS
At-home
Online Access:https://doi.org/10.1186/s12936-022-04239-x

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