Mutations of the EPHB6 receptor tyrosine kinase induce a pro-metastatic phenotype in non-small cell lung cancer.
Alterations of Eph receptor tyrosine kinases are frequent events in human cancers. Genetic variations of EPHB6 have been described but the functional outcome of these alterations is unknown. The current study was conducted to screen for the occurrence and to identify functional consequences of EPHB6...
Main Authors: | Etmar Bulk, Jun Yu, Antje Hascher, Steffen Koschmieder, Rainer Wiewrodt, Utz Krug, Bernd Timmermann, Alessandro Marra, Ludger Hillejan, Karsten Wiebe, Wolfgang E Berdel, Albrecht Schwab, Carsten Müller-Tidow |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3514309?pdf=render |
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