Intrinsic and Microenvironmental Drivers of Glioblastoma Invasion

Intrinsic and Microenvironmental Drivers of Glioblastoma Invasion

Gliomas are diffusely infiltrating brain tumors whose prognosis is strongly influenced by their extent of invasion into the surrounding brain tissue. While lower-grade gliomas present more circumscribed borders, high-grade gliomas are aggressive tumors with widespread brain infiltration and dissemin...

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Bibliographic Details
Main Authors: Emerson De Fazio, Matilde Pittarello, Alessandro Gans, Bikona Ghosh, Hasan Slika, Paolo Alimonti, Betty Tyler
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:International Journal of Molecular Sciences
Subjects:
glioma
invasion
microenvironment
molecular mechanisms
neuronal niche
astrocytes
Online Access:https://www.mdpi.com/1422-0067/25/5/2563

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