Increased Serum NSE and S100B Indicate Neuronal and Glial Alterations in Subjects Under 71 Years With Mild Neurocognitive Disorder/Mild Cognitive Impairment

Increased Serum NSE and S100B Indicate Neuronal and Glial Alterations in Subjects Under 71 Years With Mild Neurocognitive Disorder/Mild Cognitive Impairment

BackgroundMild cognitive impairment (MCI) is considered a pre-stage of different dementia syndromes. Despite diagnostic criteria refined by DSM-5 and a new term for MCI – “mild neurocognitive disorder” (mild NCD) – this diagnosis is still based on clinical criteria.MethodsTo link mild NCD to the und...

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Bibliographic Details
Main Authors: Maryna Polyakova, Karsten Mueller, Katrin Arelin, Leonie Lampe, Francisca S. Rodriguez, Tobias Luck, Jürgen Kratzsch, Karl-Titus Hoffmann, Steffi Riedel-Heller, Arno Villringer, Peter Schoenknecht, Matthias L. Schroeter
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Cellular Neuroscience
Subjects:
mild cognitive impairment
white matter hyperintensities
S100B
neuron-specific enolase
NSE
Brain-Derived Neurotrophic Factor
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2022.788150/full

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