Diagnosis and Management of Esophageal and Gastric Variceal Bleeding: Focused on 2019 KASL Clinical Practice Guidelines for Liver Cirrhosis
Varices are a frequent complication of liver cirrhosis and a major cause of mortality in patients with liver cirrhosis. Patients with decompensated cirrhosis complications have a poor prognosis and require careful management. Portal hypertension is the most common complication of liver cirrhosis,...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Jin Publishing & Printing Co.
2022-09-01
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| Series: | The Korean Journal of Gastroenterology |
| Subjects: | |
| Online Access: | https://www.kjg.or.kr/journal/view.html?uid=5744&vmd=Full |
| Summary: | Varices are a frequent complication of liver cirrhosis and a major cause of mortality in patients with liver cirrhosis. Patients with decompensated
cirrhosis complications have a poor prognosis and require careful management. Portal hypertension is the most common
complication of liver cirrhosis, which is the key determinant for varices development. Increased intrahepatic vascular resistance to
portal flow leads to the development of portal hypertension. Collateral vessels develop at the communication site between the systemic
and portal circulation with the progression of portal hypertension. Varices are the representative collaterals, develop gradually
with the progression of portal hypertension and may eventually rupture. Variceal bleeding is a major consequence of portal hypertension
and causes the death of cirrhotic patients. The present paper reviews the latest knowledge regarding the diagnosis and management
of esophageal and gastric variceal bleeding. |
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| ISSN: | 1598-9992 2233-6869 |