Diagnosis and Management of Esophageal and Gastric Variceal Bleeding: Focused on 2019 KASL Clinical Practice Guidelines for Liver Cirrhosis

Varices are a frequent complication of liver cirrhosis and a major cause of mortality in patients with liver cirrhosis. Patients with decompensated cirrhosis complications have a poor prognosis and require careful management. Portal hypertension is the most common complication of liver cirrhosis,...

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Main Authors: Min Kyung Park, Yun Bin Lee
Format: Article
Language:English
Published: Jin Publishing & Printing Co. 2022-09-01
Series:The Korean Journal of Gastroenterology
Subjects:
Online Access:https://www.kjg.or.kr/journal/view.html?uid=5744&vmd=Full
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author Min Kyung Park
Yun Bin Lee
author_facet Min Kyung Park
Yun Bin Lee
author_sort Min Kyung Park
collection DOAJ
description Varices are a frequent complication of liver cirrhosis and a major cause of mortality in patients with liver cirrhosis. Patients with decompensated cirrhosis complications have a poor prognosis and require careful management. Portal hypertension is the most common complication of liver cirrhosis, which is the key determinant for varices development. Increased intrahepatic vascular resistance to portal flow leads to the development of portal hypertension. Collateral vessels develop at the communication site between the systemic and portal circulation with the progression of portal hypertension. Varices are the representative collaterals, develop gradually with the progression of portal hypertension and may eventually rupture. Variceal bleeding is a major consequence of portal hypertension and causes the death of cirrhotic patients. The present paper reviews the latest knowledge regarding the diagnosis and management of esophageal and gastric variceal bleeding.
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spelling doaj.art-5558a41dd58540748b007843baf786952022-12-22T02:05:56ZengJin Publishing & Printing Co.The Korean Journal of Gastroenterology1598-99922233-68692022-09-0182315216010.4166/kjg.2021.113Diagnosis and Management of Esophageal and Gastric Variceal Bleeding: Focused on 2019 KASL Clinical Practice Guidelines for Liver CirrhosisMin Kyung Park 0Yun Bin Lee1https://orcid.org/0000-0002-3193-9745Department of Internal Medicine, Seoul National University Hospital, Seoul, KoreaDepartment of Internal Medicine, Seoul National University Hospital, Seoul; Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, KoreaVarices are a frequent complication of liver cirrhosis and a major cause of mortality in patients with liver cirrhosis. Patients with decompensated cirrhosis complications have a poor prognosis and require careful management. Portal hypertension is the most common complication of liver cirrhosis, which is the key determinant for varices development. Increased intrahepatic vascular resistance to portal flow leads to the development of portal hypertension. Collateral vessels develop at the communication site between the systemic and portal circulation with the progression of portal hypertension. Varices are the representative collaterals, develop gradually with the progression of portal hypertension and may eventually rupture. Variceal bleeding is a major consequence of portal hypertension and causes the death of cirrhotic patients. The present paper reviews the latest knowledge regarding the diagnosis and management of esophageal and gastric variceal bleeding.https://www.kjg.or.kr/journal/view.html?uid=5744&vmd=Fullesophageal and gastric varicesliver cirrhosisportal hypertensionhemorrhagehemostasis
spellingShingle Min Kyung Park
Yun Bin Lee
Diagnosis and Management of Esophageal and Gastric Variceal Bleeding: Focused on 2019 KASL Clinical Practice Guidelines for Liver Cirrhosis
The Korean Journal of Gastroenterology
esophageal and gastric varices
liver cirrhosis
portal hypertension
hemorrhage
hemostasis
title Diagnosis and Management of Esophageal and Gastric Variceal Bleeding: Focused on 2019 KASL Clinical Practice Guidelines for Liver Cirrhosis
title_full Diagnosis and Management of Esophageal and Gastric Variceal Bleeding: Focused on 2019 KASL Clinical Practice Guidelines for Liver Cirrhosis
title_fullStr Diagnosis and Management of Esophageal and Gastric Variceal Bleeding: Focused on 2019 KASL Clinical Practice Guidelines for Liver Cirrhosis
title_full_unstemmed Diagnosis and Management of Esophageal and Gastric Variceal Bleeding: Focused on 2019 KASL Clinical Practice Guidelines for Liver Cirrhosis
title_short Diagnosis and Management of Esophageal and Gastric Variceal Bleeding: Focused on 2019 KASL Clinical Practice Guidelines for Liver Cirrhosis
title_sort diagnosis and management of esophageal and gastric variceal bleeding focused on 2019 kasl clinical practice guidelines for liver cirrhosis
topic esophageal and gastric varices
liver cirrhosis
portal hypertension
hemorrhage
hemostasis
url https://www.kjg.or.kr/journal/view.html?uid=5744&vmd=Full
work_keys_str_mv AT minkyungpark diagnosisandmanagementofesophagealandgastricvaricealbleedingfocusedon2019kaslclinicalpracticeguidelinesforlivercirrhosis
AT yunbinlee diagnosisandmanagementofesophagealandgastricvaricealbleedingfocusedon2019kaslclinicalpracticeguidelinesforlivercirrhosis