Cell Therapy for Anal Sphincter Incontinence: Where Do We Stand?

Cell Therapy for Anal Sphincter Incontinence: Where Do We Stand?

Anal sphincter incontinence is a chronic disease, which dramatically impairs quality of life and induces high costs for the society. Surgery, considered as the best curative option, shows a disappointing success rate. Stem/progenitor cell therapy is pledging, for anal sphincter incontinence, a subst...

Full description

Bibliographic Details
Main Authors:	Alexandre Balaphas, Jeremy Meyer, Raphael P. H. Meier, Emilie Liot, Nicolas C. Buchs, Bruno Roche, Christian Toso, Leo H. Bühler, Carmen Gonelle-Gispert, Frédéric Ris
Format:	Article
Language:	English
Published:	MDPI AG 2021-08-01
Series:	Cells
Subjects:	anal incontinence fecal incontinence stem cell progenitor cell mulitipotent cell myoblast
Online Access:	https://www.mdpi.com/2073-4409/10/8/2086

Similar Items

Prevalence of Anal Incontinence and Constipation in Female Patients with Urinary Incontinence
by: Musa Saraçoğlu, et al.
Published: (2018-04-01)

Differentiation of Adipose-Derived Stem Cells into Smooth Muscle Cells in an Internal Anal Sphincter-Targeting Anal Incontinence Rat Model
by: Minsung Kim, et al.
Published: (2023-02-01)

EXPERIENCE OF APPLICATION OF VOLUME FORMING AGENT «DAM+» IN TREATMENT OF ANAL INCONTINENCE ASSOCIATED WITH INCOMPETENCE AND TRAUMA OF ANAL SPHINCTER
by: I. A. Komissarov, et al.
Published: (2016-10-01)

The long-term prevalence of anal incontinence in women with and without obstetric anal sphincter injuries
by: Rebecca Everist, et al.
Published: (2023-03-01)

Prevalence and Risk Factors of Anal and Fecal Incontinence in Japanese Medical Personnel
by: Kotaro Maeda, et al.
Published: (2021-10-01)

Anal Sphincter Injuries During Hemorrhoidectomy: A Multi Center Study
by: Rasoul Azizi, et al.
Published: (2012-09-01)

Usefulness of An Anal Sphincter Injury Mouse Model by Means of a Balloon Catheter and a New Method of Evaluating Anal Sphincter Function
by: Ryohei Yukimoto, et al.
Published: (2022-03-01)

A systematic review of translation and experimental studies on internal anal sphincter for fecal incontinence
by: Minsung Kim, et al.
Published: (2022-06-01)

Postpartum anal incontinence
by: A. L. Petrushin, et al.
Published: (2019-05-01)

Patient’s characteristics and incidence of fecal incontinence after primary repair of Obstetric Anal Sphincter Injuries (OASIS) at three Indonesian tertiary hospitals in 2014–2016
by: Suskhan Djusad, et al.
Published: (2020-07-01)

Anal Sphincter Function After Hemorrhoidectomy
by: A. M. Kuzminov, et al.
Published: (2019-06-01)

Fistulotomy Around The Sphincter (FATS) Procedure: A Simple New Sphincter-Sparing Concept to Treat High Fistula-In-Ano
by: Pankaj Garg
Published: (2018-08-01)

DO CHANGES IN ANAL SPHINCTER ANATOMY CORRELATE WITH ANAL FUNCTION IN WOMEN WITH A HISTORY OF VAGINAL DELIVERY?
by: Sthela Maria MURAD-REGADAS, et al.

Long-term results from modified sphincteroplasty in patients with traumatic sphincter injury: a retrospective study
by: Mustafa Berkesoglu, et al.
Published: (2021-01-01)

Fecal incontinence [electronic resource] : diagnosis and treatment /
by: Ratto, Carlo, et al.
Published: (2007)

Relationship between episiotomy and fecal incontinence after delivery
by: Hajar Khazraei, et al.
Published: (2020-09-01)

Effectiveness of the ligation of intersphincteric fistula tract (LIFT) in the treatment of anal fistula: initial results
by: Sergio Danilo Tanahara TOMIYOSHI, et al.
Published: (2014-06-01)

The Japanese Extracted Herbal Medicine Daikenchuto Increases the Contractile Activity of the Internal Anal Sphincter Muscle in Conscious Dogs
by: Kotaro Maeda, et al.
Published: (2020-10-01)

Anal incontinence and unrecognized anal sphincter injuries after vaginal delivery– a cross-sectional study in Norway
by: Matilde Risopatron Berg, et al.
Published: (2020-06-01)

Simple Anal Reinforcement with Anal Encirclement Using an Artificial Ligament in Patients with fecal Incontinence: A Single-center Observational Study
by: Tatsuya Abe, et al.
Published: (2022-07-01)

Combination of laser and human adipose-derived stem cells in repair of rabbit anal sphincter injury: a new therapeutic approach
by: Arash Sarveazad, et al.
Published: (2019-12-01)

Incontinence, bladder neck mobility, and sphincter ruptures in primiparous women
by: Jundt K, et al.
Published: (2010-06-01)

ELECTROMIOSTIMULATION OF ANAL SPHINCTER AS A TREATMENT OPTION FOR FECAL INCONTINENCE AFTER ULTRA-LOW ANTERIOR RESECTION
by: Y. A. Barsukov, et al.
Published: (2015-02-01)

SECCA procedure for anal incontinence and antibiotic treatment: a case report of anal abscess
by: Francesca Mandolfino, et al.
Published: (2018-08-01)

The Effect of Tissue Stromal Vascular Fraction as Compared to Cellular Stromal Vascular Fraction to Treat Anal Sphincter Incontinence
by: Wenbin Chen, et al.
Published: (2022-12-01)

Skeletal muscle-derived cell implantation for the treatment of sphincter-related faecal incontinence
by: Andrea Frudinger, et al.
Published: (2018-09-01)

Evaluation of Fistulotomy with Immediate Sphincteric Reconstruction in the Treatment of High Transsphincteric Perianal Fistula
by: Yasser A. Orban, et al.
Published: (2021-09-01)

SPHINCTEROPLASTY IN THE TREATMENT OF ANAL INCONTINENCE ON THE BASIS OF NECROTIZING FASCIITIS
by: O. E. Kanikovskyi, et al.
Published: (2019-10-01)

Modified Perineal Reconstruction Combined with Anal Sphincter Repair for Obstetric Anal Sphincter Injuries
by: Wang X, et al.
Published: (2022-07-01)

Combined 3D Endoanal Ultrasound and Transperineal Ultrasound Improves the Detection of Anal Sphincter Defects
by: Dan Carter, et al.
Published: (2023-02-01)

Anal Incontinence after Anterior Rectum Resection in Cancer Patients
by: O. I. Kit, et al.
Published: (2020-04-01)

The effect of Trolox on the rabbit anal sphincterotomy repair
by: Arash Sarveazad, et al.
Published: (2023-06-01)

Disorders of the pelvic floor and anal sphincters; a gastroenterologist’s perspective
by: Eamonn M.M. Quigley, MD FRCP FACP FACG FRCPI
Published: (2013-03-01)

Application of Bifurcated Semitendinosus Muscle Transposition for Treatment of Fecal Incontinence in Two Dogs
by: Mu-Young Kim, et al.
Published: (2023-02-01)

Development and Validation of the Turkish Version of the Colorectal Anal Distress Scale-8
by: Serdar AYDIN, et al.
Published: (2017-01-01)

Two-dimensional Endoanal Ultrasound Scan Correlates with External Anal Sphincter Structure and Function, but not with Puborectalis
by: Kumaran Thiruppathy, et al.
Published: (2015-12-01)

Avaliação da qualidade de vida na incontinência anal: validação do questionário FIQL (Fecal Incontinence Quality of Life) Evaluation of quality of life in anal incontinence: validation of the questionnaire FIQL (Fecal Incontinence Quality of Life)
by: Sonia Ahlaim Ibrahim Yusuf, et al.
Published: (2004-09-01)

Japanese Practice Guidelines for Fecal Incontinence Part 1-Definition, Epidemiology, Etiology, Pathophysiology and Causes, Risk Factors, Clinical Evaluations, and Symptomatic Scores and QoL Questionnaire for Clinical Evaluations-English Version
by: Kotaro Maeda, et al.
Published: (2021-01-01)

Anal Sphincter Augmentation using Biological Material
by: Nasra N Alam, et al.
Published: (2015-11-01)

Long-term Efficacy and Safety of Controlled Manual Anal Dilatation in the Treatment of Chronic Anal Fissures: A Single-center Observational Study
by: Tatsuya Abe, et al.
Published: (2023-10-01)