The Pediatric Proton and Photon Therapy Comparison Cohort: Study Design for a Multicenter Retrospective Cohort to Investigate Subsequent Cancers After Pediatric Radiation Therapy

Purpose: The physical properties of protons lower doses to surrounding normal tissues compared with photons, potentially reducing acute and long-term adverse effects, including subsequent cancers. The magnitude of benefit is uncertain, however, and currently based largely on modeling studies. Despit...

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Main Authors: Amy Berrington de González, DPhil, Todd M. Gibson, PhD, Choonsik Lee, PhD, Paul S. Albert, PhD, Keith T. Griffin, MS, Cari Meinhold Kitahara, PhD, Danping Liu, PhD, Matthew M. Mille, PhD, Jungwook Shin, PhD, Benjamin V.M. Bajaj, PhD, Tristin E. Flood, MS, Sara L. Gallotto, MS, Harald Paganetti, PhD, Safia K. Ahmed, MD, Bree R. Eaton, MD, Daniel J. Indelicato, MD, Sarah A. Milgrom, MD, Joshua D. Palmer, MD, Sujith Baliga, MD, Matthew M. Poppe, MD, Derek S. Tsang, MD, Kenneth Wong, MD, Torunn I. Yock, MD
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Advances in Radiation Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S2452109423001021