Elecampane (<i>Inula helenium</i>) Root Extract and Its Major Sesquiterpene Lactone, Alantolactone, Inhibit Adipogenesis of 3T3-L1 Preadipocytes

Elecampane (<i>Inula helenium</i>) Root Extract and Its Major Sesquiterpene Lactone, Alantolactone, Inhibit Adipogenesis of 3T3-L1 Preadipocytes

Recent studies have shown that Nur77 and AMPKα play an important role in regulating adipogenesis and isoalantolactone (ISO) dual-targeting AMPKα and Nur77 inhibits adipogenesis. In this study, we hypothesized that <i>Inula helenium</i> (elecampane) root extract (IHE), which contains two...

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Bibliographic Details
Main Authors: Yeon-Seop Jung, Yun-Jeong Jeong, Joung-Hee Kim, Chang-Hwan Jeon, Syng-Ook Lee
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Molecules
Subjects:
adipogenesis
Nur77
AMPKα
alantolactone
<i>Inula helenium</i>
elecampane
Online Access:https://www.mdpi.com/1420-3049/27/15/4765

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